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Bioorganic & Medicinal Chemistry Letters|October 10, 2002
Design and synthesis of xanthine analogues as potent and selective PDE5 inhibitorsYuguang Wang, Samuel Chackalamannil, Zhiyong Hu, et al.Bioorganic & Medicinal Chemistry Letters|October 23, 2012
Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic painStephanie Brumfield, Peter Korakas, Lisa S Silverman, et al.Bioorganic & Medicinal Chemistry Letters|November 3, 2006
Discovery of gamma-secretase inhibitors efficacious in a transgenic animal model of Alzheimer's diseaseTheodros Asberom, Zhiqiang Zhao, Thomas A Bara, et al.Circulation|March 1, 1996
Effects of subtype-selective and balanced angiotensin II receptor antagonists in a porcine coronary artery model of vascular restenosisW R Huckle, M D Drag, W R Acker, et al.Journal of Medicinal Chemistry|January 2, 2010
Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitorsYu-Sen Wang, Corey Strickland, Johannes H Voigt, et al.Bioorganic & Medicinal Chemistry Letters|October 6, 2009
Tetrahydroquinoline sulfonamides as vasopressin 1b receptor antagonistsJack D Scott, Michael W Miller, Sarah W Li, et al.Bioorganic & Medicinal Chemistry Letters|April 20, 2005
Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male EDCraig D Boyle, Ruo Xu, Theodros Asberom, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-Secretase Inhibitor for the Treatment of Alzheimer's DiseaseWen-Lian Wu, Martin Domalski, Duane A Burnett, et al.Bioorganic & Medicinal Chemistry Letters|April 3, 2009
The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxietyGinny D Ho, John Anthes, Ana Bercovici, et al.Life Sciences|January 1, 1996
Pharmacology of L-744,453, a novel nonpeptidyl endothelin antagonistD L Williams, K L Murphy, N A Nolan, et al.Pageof 30