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Acta Neuropathologica|July 25, 2022
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTDClaudia S Bauer, Rebecca N Cohen, Francesca Sironi, et al.
Molecular and Cellular Neurosciences|June 23, 2004
p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosisSteven Ackerley, Andrew J Grierson, Steven Banner, et al.
Plos One|March 31, 2010
Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)Laura E Cox, Laura Ferraiuolo, Emily F Goodall, et al.
Frontiers in Cellular Neuroscience|January 9, 2023
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturationClaudia S Bauer, Christopher P Webster, Allan C Shaw, et al.
The EMBO Journal|June 24, 2016
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagyChristopher P Webster, Emma F Smith, Claudia S Bauer, et al.
JCI Insight|July 14, 2026
HDAC6 inhibition alleviates mitochondrial trafficking in novel models of Charcot-Marie-Tooth Disease Type 2ALydia H Jestice, Larissa Butler, Rebecca A Lea, et al.
Life Science Alliance|May 14, 2022
C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neuronsPaolo M Marchi, Lara Marrone, Laurent Brasseur, et al.
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