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Current Topics in Medicinal Chemistry|November 6, 2007
An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmesJeffrey S Albert, Niklas Blomberg, Alexander L Breeze, et al.Pain|October 9, 2024
GPR35 agonists inhibit TRPA1-mediated colonic nociception through suppression of substance P releaseRohit A Gupta, James P Higham, Abigail Pearce, et al.European Journal of Endocrinology|December 20, 2023
A novel somatostatin receptor ligand for human ACTH - and GH -secreting pituitary adenomasDaniela Regazzo, Serena Avallone, Cliona P MacSweeney, et al.Nature Communications|December 27, 2024
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptorThomas L Williams, Grégory Verdon, Rhoda E Kuc, et al.Nature|April 26, 2016
Extra-helical binding site of a glucagon receptor antagonistAli Jazayeri, Andrew S Doré, Daniel Lamb, et al.Journal of Medicinal Chemistry|June 20, 2020
Structure-Based Drug Discovery of N-((R)-3-(7-Methyl-1H-indazol-5-yl)-1-oxo-1-(((S)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of MigraineSarah J Bucknell, Mark A Ator, Alastair J H Brown, et al.Nature|July 13, 2017
Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonistAli Jazayeri, Mathieu Rappas, Alastair J H Brown, et al.Nature|June 1, 2017
Crystal structure of the GLP-1 receptor bound to a peptide agonistAli Jazayeri, Mathieu Rappas, Alastair J H Brown, et al.Journal of Medicinal Chemistry|April 5, 2017
Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo EfficacyWilliam McCoull, Andrew Bailey, Peter Barton, et al.Journal of Medicinal Chemistry|June 27, 2014
Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonistsWilliam McCoull, Peter Barton, Alastair J H Brown, et al.Pageof 31