Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

J H Freisheim

Showing results (31-40 of 88) with videos related to

Pageof 9
Sort By:
The Journal of Biological Chemistry|September 25, 1978
Dihydrofolate reductase from amethopterin-resistant Lactobacillus casei. Sequences of the cyanogen bromide peptides and complete sequences of the enzymeJ H Freisheim, K G Bitar, A V Reddy, et al.
Biochemistry|January 18, 1983
Fluorescent analogues of methotrexate: characterization and interaction with dihydrofolate reductaseA A Kumar, R J Kempton, G M Anstead, et al.
Biochemical Pharmacology|November 3, 1992
Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolatesX Wang, F Shen, J H Freisheim, et al.
Biochemistry|May 17, 1988
Expression and site-directed mutagenesis of human dihydrofolate reductaseN J Prendergast, T J Delcamp, P L Smith, et al.
Journal of Medicinal Chemistry|July 1, 1984
Methotrexate analogues. 23. Synthesis, dihydrofolate reductase affinity, cytotoxicity, and in vivo antitumor activity of some putative degradation products of methotrexate-poly(L-lysine) conjugatesA Rosowsky, R A Forsch, J H Freisheim, et al.
Biochemical Pharmacology|June 15, 1984
A fluorescent analogue of methotrexate as a probe for folate antagonist molecular receptorsS S Susten, R J Kempton, A M Black, et al.
Biochemistry|February 1, 1983
Purification and characterization of dihydrofolate reductase from methotrexate-resistant human lymphoblastoid cellsT J Delcamp, S S Susten, D T Blankenship, et al.
Biochemistry|April 14, 1992
Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiencyJ R Appleman, J T Tsay, J H Freisheim, et al.
Journal of Molecular Biology|March 24, 1995
Contributions of tryptophan 24 and glutamate 30 to binding long-lived water molecules in the ternary complex of human dihydrofolate reductase with methotrexate and NADPH studied by site-directed mutagenesis and nuclear magnetic resonance spectroscopyE M Meiering, H Li, T J Delcamp, et al.
The Journal of Biological Chemistry|July 25, 1988
Kinetics of the formation and isomerization of methotrexate complexes of recombinant human dihydrofolate reductaseJ R Appleman, N Prendergast, T J Delcamp, et al.
Pageof 9

Showing results (31-40 of 88) with videos related to

Sort By:
Pageof 9
The Journal of Biological Chemistry|September 25, 1978
Dihydrofolate reductase from amethopterin-resistant Lactobacillus casei. Sequences of the cyanogen bromide peptides and complete sequences of the enzymeJ H Freisheim, K G Bitar, A V Reddy, et al.
Biochemistry|January 18, 1983
Fluorescent analogues of methotrexate: characterization and interaction with dihydrofolate reductaseA A Kumar, R J Kempton, G M Anstead, et al.
Biochemical Pharmacology|November 3, 1992
Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolatesX Wang, F Shen, J H Freisheim, et al.
Biochemistry|May 17, 1988
Expression and site-directed mutagenesis of human dihydrofolate reductaseN J Prendergast, T J Delcamp, P L Smith, et al.
Journal of Medicinal Chemistry|July 1, 1984
Methotrexate analogues. 23. Synthesis, dihydrofolate reductase affinity, cytotoxicity, and in vivo antitumor activity of some putative degradation products of methotrexate-poly(L-lysine) conjugatesA Rosowsky, R A Forsch, J H Freisheim, et al.
Biochemical Pharmacology|June 15, 1984
A fluorescent analogue of methotrexate as a probe for folate antagonist molecular receptorsS S Susten, R J Kempton, A M Black, et al.
Biochemistry|February 1, 1983
Purification and characterization of dihydrofolate reductase from methotrexate-resistant human lymphoblastoid cellsT J Delcamp, S S Susten, D T Blankenship, et al.
Biochemistry|April 14, 1992
Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiencyJ R Appleman, J T Tsay, J H Freisheim, et al.
Journal of Molecular Biology|March 24, 1995
Contributions of tryptophan 24 and glutamate 30 to binding long-lived water molecules in the ternary complex of human dihydrofolate reductase with methotrexate and NADPH studied by site-directed mutagenesis and nuclear magnetic resonance spectroscopyE M Meiering, H Li, T J Delcamp, et al.
The Journal of Biological Chemistry|July 25, 1988
Kinetics of the formation and isomerization of methotrexate complexes of recombinant human dihydrofolate reductaseJ R Appleman, N Prendergast, T J Delcamp, et al.
Pageof 9