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Journal of Medicinal Chemistry|May 16, 2003
Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1BGang Liu, Bruce G Szczepankiewicz, Zhonghua Pei, et al.The Journal of Clinical Investigation|May 8, 2025
NK cell activation and CD4 T cell α4β7 expression are associated with susceptibility to HIV-1Kawthar Machmach, Kombo F N'guessan, Rohit Farmer, et al.Bioorganic & Medicinal Chemistry Letters|February 6, 2007
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hitBradley J Backes, Kenton Longenecker, Gregory L Hamilton, et al.Journal of Medicinal Chemistry|October 27, 2006
Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetesZhonghua Pei, Xiaofeng Li, Thomas W von Geldern, et al.Journal of Medicinal Chemistry|June 9, 2006
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitorsZhonghua Pei, Xiaofeng Li, Kenton Longenecker, et al.Molecular Cancer Therapeutics|June 16, 2005
Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivoYan Luo, Alexander R Shoemaker, Xuesong Liu, et al.Journal of Medicinal Chemistry|October 13, 2006
Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetesDavid J Madar, Hana Kopecka, Daisy Pireh, et al.Pageof 6