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J J McGuire

Showing results (31-40 of 75) with videos related to

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Journal of Medicinal Chemistry|August 24, 2000
Effect of C9-methyl substitution and C8-C9 conformational restriction on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidinesA Gangjee, Y Zeng, J J McGuire, et al.
Journal of Medicinal Chemistry|January 5, 1996
Synthesis and biological evaluation of DL-4,4-difluoroglutamic acid and DL-gamma,gamma-difluoromethotrexateT Tsukamoto, T Kitazume, J J McGuire, et al.
Archives of Biochemistry and Biophysics|July 2, 1998
Mechanism-based inhibition of human folylpolyglutamate synthetase: design, synthesis, and biochemical characterization of a phosphapeptide mimic of the tetrahedral intermediateT Tsukamoto, W H Haile, J J McGuire, et al.
Biochemistry|December 13, 1988
Dihydrofolate synthetase and folylpolyglutamate synthetase: direct evidence for intervention of acyl phosphate intermediatesR V Banerjee, B Shane, J J McGuire, et al.
Leukemia|February 1, 1987
Effects of methotrexate and of the "nonclassical" folate antagonist trimetrexate on human leukemia cellsS Rodenhuis, J J McGuire, W L Sawicki, et al.
Biochemical Pharmacology|March 7, 1997
Mechanisms of acquired resistance to modulation of 5-fluorouracil by leucovorin in HCT-8 human ileocecal carcinoma cellsK Lu, J J McGuire, H K Slocum, et al.
The Journal of Biological Chemistry|August 25, 1990
DL-3,3-difluoroglutamate: an enhancer of folylpolyglutamate elongationJ J McGuire, W H Haile, P Bey, et al.
Advances in Experimental Medicine and Biology|January 1, 1983
In vitro methotrexate polyglutamate synthesis by rat liver folylpolyglutamate synthetase and inhibition by bromosulfophthaleinJ J McGuire, P Hsieh, J K Coward, et al.
Cancer Research|October 1, 1989
Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drugG Pizzorno, Y M Chang, J J McGuire, et al.
The Journal of Biological Chemistry|June 25, 1980
Enzymatic synthesis of folylpolyglutamates. Characterization of the reaction and its productsJ J McGuire, P Hsieh, J K Coward, et al.
Pageof 8

Showing results (31-40 of 75) with videos related to

Sort By:
Pageof 8
Journal of Medicinal Chemistry|August 24, 2000
Effect of C9-methyl substitution and C8-C9 conformational restriction on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidinesA Gangjee, Y Zeng, J J McGuire, et al.
Journal of Medicinal Chemistry|January 5, 1996
Synthesis and biological evaluation of DL-4,4-difluoroglutamic acid and DL-gamma,gamma-difluoromethotrexateT Tsukamoto, T Kitazume, J J McGuire, et al.
Archives of Biochemistry and Biophysics|July 2, 1998
Mechanism-based inhibition of human folylpolyglutamate synthetase: design, synthesis, and biochemical characterization of a phosphapeptide mimic of the tetrahedral intermediateT Tsukamoto, W H Haile, J J McGuire, et al.
Biochemistry|December 13, 1988
Dihydrofolate synthetase and folylpolyglutamate synthetase: direct evidence for intervention of acyl phosphate intermediatesR V Banerjee, B Shane, J J McGuire, et al.
Leukemia|February 1, 1987
Effects of methotrexate and of the "nonclassical" folate antagonist trimetrexate on human leukemia cellsS Rodenhuis, J J McGuire, W L Sawicki, et al.
Biochemical Pharmacology|March 7, 1997
Mechanisms of acquired resistance to modulation of 5-fluorouracil by leucovorin in HCT-8 human ileocecal carcinoma cellsK Lu, J J McGuire, H K Slocum, et al.
The Journal of Biological Chemistry|August 25, 1990
DL-3,3-difluoroglutamate: an enhancer of folylpolyglutamate elongationJ J McGuire, W H Haile, P Bey, et al.
Advances in Experimental Medicine and Biology|January 1, 1983
In vitro methotrexate polyglutamate synthesis by rat liver folylpolyglutamate synthetase and inhibition by bromosulfophthaleinJ J McGuire, P Hsieh, J K Coward, et al.
Cancer Research|October 1, 1989
Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drugG Pizzorno, Y M Chang, J J McGuire, et al.
The Journal of Biological Chemistry|June 25, 1980
Enzymatic synthesis of folylpolyglutamates. Characterization of the reaction and its productsJ J McGuire, P Hsieh, J K Coward, et al.
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