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Pharmacological Research|August 31, 2015
The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazonesPatric J Jansson, Danuta S Kalinowski, Darius J R Lane, et al.Current Medicinal Chemistry|July 8, 2017
Exploiting Cancer Metal Metabolism using Anti-Cancer Metal- Binding AgentsAngelica M Merlot, Danuta S Kalinowski, Zaklina Kovacevic, et al.Biochimica Et Biophysica Acta. Molecular Basis of Disease|October 25, 2024
Cancer stem cells: Masters of all traitsLionel Y W Leck, Yomna S Abd El-Aziz, Kelly J McKelvey, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|January 23, 2021
Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stromaBekesho Geleta, Kyung Chan Park, Patric J Jansson, et al.Pharmacological Research|May 27, 2023
Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancerFaten Shehadeh-Tout, Heloisa H Milioli, Suraya Roslan, et al.Biochimica Et Biophysica Acta. Molecular Basis of Disease|June 2, 2020
Acireductone dioxygenase 1 (ADI1) is regulated by cellular iron by a mechanism involving the iron chaperone, PCBP1, with PCBP2 acting as a potential co-chaperoneDong-Hun Bae, Darius J R Lane, Aritee R Siafakas, et al.Biochemical Pharmacology|April 10, 2016
Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinaseAngelica M Merlot, Nurul H Shafie, Yu Yu, et al.Molecular Pharmacology|October 18, 2012
The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of actionGoldie Y L Lui, Peyman Obeidy, Samuel J Ford, et al.Biochimica Et Biophysica Acta|February 5, 2016
Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signalingJasmina Paluncic, Zaklina Kovacevic, Patric J Jansson, et al.Biochimica Et Biophysica Acta. Molecular Cell Research|November 14, 2023
Inhibition of autophagy initiation: A novel strategy for oral squamous cell carcinomasYomna S Abd El-Aziz, Matthew J McKay, Mark P Molloy, et al.Pageof 10