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Journal of Medicinal Chemistry|April 14, 2017
Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L BromodomainsLéa Bouché, Clara D Christ, Stephan Siegel, et al.American Journal of Physiology. Endocrinology and Metabolism|September 11, 2019
Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in miceSara L Jepsen, Kaare V Grunddal, Nicolai J Wewer Albrechtsen, et al.SLAS Discovery : Advancing Life Sciences R & D|June 22, 2021
Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput ScreeningStefan Gradl, Holger Steuber, Joerg Weiske, et al.Blood|October 4, 2017
Effective "activated PI3Kδ syndrome"-targeted therapy with the PI3Kδ inhibitor leniolisibV Koneti Rao, Sharon Webster, Virgil A S H Dalm, et al.Journal of Medicinal Chemistry|April 15, 2016
Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2Erik Eggert, Roman C Hillig, Silke Koehr, et al.Journal of Pharmaceutical Sciences|October 5, 2007
N-in-1 dosing pharmacokinetics in drug discovery: experience, theoretical and practical considerationsKan He, Mingxin Qian, Harvey Wong, et al.Journal of Medicinal Chemistry|September 16, 2008
Potent, orally bioavailable delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (ADL5859)Bertrand Le Bourdonnec, Rolf T Windh, Christopher W Ajello, et al.Bioorganic & Medicinal Chemistry Letters|April 10, 2007
CC chemokine receptor-3 (CCR3) antagonists: improving the selectivity of DPC168 by reducing central ring lipophilicityJames R Pruitt, Douglas G Batt, Dean A Wacker, et al.Journal of Medicinal Chemistry|July 27, 2001
Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro and in vivoC B Xue, M E Voss, D J Nelson, et al.Pageof 24