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J N Champness

Showing results (11-20 of 23) with videos related to

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FEBS Letters|August 19, 1999
2.0 A X-ray structure of the ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogueD K Stammers, A Achari, D O Somers, et al.
Biochemical Society Transactions|February 5, 1998
Structure-specificity features of HSV-1 thymidine kinasesJ S Evans, K P Lock, B A Levine, et al.
Journal of Molecular Biology|March 20, 1993
Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductaseD K Stammers, C Delves, S Ballantine, et al.
FEBS Letters|April 6, 1981
The binding of trimethoprim to bacterial dihydrofolate reductaseD J Baker, C R Beddell, J N Champness, et al.
FEBS Letters|February 16, 1999
Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovirM S Bennett, F Wien, J N Champness, et al.
FEBS Letters|June 22, 1987
The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzymeD K Stammers, J N Champness, C R Beddell, et al.
The Journal of General Virology|September 25, 1998
Herpesviral thymidine kinases: laxity and resistance by designJ S Evans, K P Lock, B A Levine, et al.
Journal of Medicinal Chemistry|October 23, 1998
5-Substituted pyrimidines with a 1,5-anhydro-2, 3-dideoxy-D-arabino-hexitol moiety at N-1: synthesis, antiviral activity, conformational analysis, and interaction with viral thymidine kinaseT Ostrowski, B Wroblowski, R Busson, et al.
Journal of Medicinal Chemistry|November 12, 1993
Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes virusesD L Selwood, S R Challand, J N Champness, et al.
Proteins|August 26, 1998
Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligandsJ N Champness, M S Bennett, F Wien, et al.
Pageof 3

Showing results (11-20 of 23) with videos related to

Sort By:
Pageof 3
FEBS Letters|August 19, 1999
2.0 A X-ray structure of the ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogueD K Stammers, A Achari, D O Somers, et al.
Biochemical Society Transactions|February 5, 1998
Structure-specificity features of HSV-1 thymidine kinasesJ S Evans, K P Lock, B A Levine, et al.
Journal of Molecular Biology|March 20, 1993
Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductaseD K Stammers, C Delves, S Ballantine, et al.
FEBS Letters|April 6, 1981
The binding of trimethoprim to bacterial dihydrofolate reductaseD J Baker, C R Beddell, J N Champness, et al.
FEBS Letters|February 16, 1999
Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovirM S Bennett, F Wien, J N Champness, et al.
FEBS Letters|June 22, 1987
The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzymeD K Stammers, J N Champness, C R Beddell, et al.
The Journal of General Virology|September 25, 1998
Herpesviral thymidine kinases: laxity and resistance by designJ S Evans, K P Lock, B A Levine, et al.
Journal of Medicinal Chemistry|October 23, 1998
5-Substituted pyrimidines with a 1,5-anhydro-2, 3-dideoxy-D-arabino-hexitol moiety at N-1: synthesis, antiviral activity, conformational analysis, and interaction with viral thymidine kinaseT Ostrowski, B Wroblowski, R Busson, et al.
Journal of Medicinal Chemistry|November 12, 1993
Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes virusesD L Selwood, S R Challand, J N Champness, et al.
Proteins|August 26, 1998
Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligandsJ N Champness, M S Bennett, F Wien, et al.
Pageof 3