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Bioorganic & Medicinal Chemistry Letters|May 16, 2006
Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitorsNigel S Watson, David Brown, Matthew Campbell, et al.Journal of Medicinal Chemistry|December 20, 2019
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity TargetZoë A Henley, Augustin Amour, Nick Barton, et al.Journal of Medicinal Chemistry|August 14, 2020
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine GliomaDavid Smil, Jong Fu Wong, Eleanor P Williams, et al.Journal of Medicinal Chemistry|August 25, 2015
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory DiseaseKenneth Down, Augustin Amour, Ian R Baldwin, et al.Antimicrobial Agents and Chemotherapy|November 25, 2004
Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimenSimon J F Macdonald, Keith G Watson, Rachel Cameron, et al.Journal of Medicinal Chemistry|April 15, 2005
Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenzaSimon J F Macdonald, Rachel Cameron, Derek A Demaine, et al.Journal of Medicinal Chemistry|September 13, 2021
Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding ModeKenneth Down, Augustin Amour, Niall A Anderson, et al.Pageof 2