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ACS Medicinal Chemistry Letters|February 16, 2017
Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of SchizophreniaMichael R Wood, Meredith J Noetzel, Bruce J Melancon, et al.Bioorganic & Medicinal Chemistry Letters|October 18, 2015
Acyl dihydropyrazolo[1,5-a]pyrimidinones as metabotropic glutamate receptor 5 positive allosteric modulatorsChrysa Malosh, Mark Turlington, Thomas M Bridges, et al.Journal of Medicinal Chemistry|August 17, 2013
Dihydrothiazolopyridone derivatives as a novel family of positive allosteric modulators of the metabotropic glutamate 5 (mGlu5) receptorJosé Manuel Bartolomé-Nebreda, Susana Conde-Ceide, Francisca Delgado, et al.Journal of Medicinal Chemistry|June 11, 2014
Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu₅)Mark Turlington, Chrysa Malosh, Jon Jacobs, et al.Bioorganic & Medicinal Chemistry Letters|May 18, 2016
Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine coreMichael R Wood, Meredith J Noetzel, Julie L Engers, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|June 23, 2012
Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal modelsGregory J Digby, Meredith J Noetzel, Michael Bubser, et al.ACS Chemical Neuroscience|December 11, 2024
Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical TrialsMichael S Poslunsey, Michael R Wood, Changho Han, et al.American Journal of Hematology|July 22, 2014
Silent cerebral infarction, income, and grade retention among students with sickle cell anemiaAllison A King, Mark J Rodeghier, Julie Ann Panepinto, et al.Blood|November 19, 2011
Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, sex, and relative high systolic blood pressureMichael R DeBaun, Sharada A Sarnaik, Mark J Rodeghier, et al.The New England Journal of Medicine|August 21, 2014
Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemiaMichael R DeBaun, Mae Gordon, Robert C McKinstry, et al.Pageof 10