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Bioorganic & Medicinal Chemistry Letters
|
May 27, 2021
Identification of aryl sulfonamides as novel and potent inhibitors of Na<sub>V</sub>1.5
Shaoyi Sun, Qi Jia, Alla Y Zenova, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models
Thilo Focken, Shifeng Liu, Navjot Chahal, et al.
Journal of Medicinal Chemistry
|
September 19, 2019
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na<sub>V</sub>1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy
Thilo Focken, Kristen Burford, Michael E Grimwood, et al.
Journal of Medicinal Chemistry
|
April 4, 2019
Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na<sub>v</sub>1.7 Inhibitors for the Treatment of Chronic Pain
Steven J McKerrall, Teresa Nguyen, Kwong Wah Lai, et al.
Science (New York, N.Y.)
|
December 19, 2015
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist
Shivani Ahuja, Susmith Mukund, Lunbin Deng, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2024
Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na<sub>V</sub>1.7
Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, et al.
Journal of Medicinal Chemistry
|
May 9, 2018
Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa<sub>V</sub>1.7 Inhibitors for the Treatment of Pain
Thilo Focken, Sultan Chowdhury, Alla Zenova, et al.
Elife
|
March 2, 2022
NBI-921352, a first-in-class, Na<sub>V</sub>1.6 selective, sodium channel inhibitor that prevents seizures in <i>Scn8a</i> gain-of-function mice, and wild-type mice and rats
J P Johnson, Thilo Focken, Kuldip Khakh, et al.
Journal of Medicinal Chemistry
|
March 8, 2021
Discovery of Acyl-sulfonamide Na<sub>v</sub>1.7 Inhibitors GDC-0276 and GDC-0310
Brian S Safina, Steven J McKerrall, Shaoyi Sun, et al.
Page
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Search research articles
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Showing results (281-290 of 289) with videos related to
Sort By:
Page
of 29
You have reached the last page of results.
This site can display upto 289 results.
Bioorganic & Medicinal Chemistry Letters
|
May 27, 2021
Identification of aryl sulfonamides as novel and potent inhibitors of Na<sub>V</sub>1.5
Shaoyi Sun, Qi Jia, Alla Y Zenova, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models
Thilo Focken, Shifeng Liu, Navjot Chahal, et al.
Journal of Medicinal Chemistry
|
September 19, 2019
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na<sub>V</sub>1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy
Thilo Focken, Kristen Burford, Michael E Grimwood, et al.
Journal of Medicinal Chemistry
|
April 4, 2019
Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na<sub>v</sub>1.7 Inhibitors for the Treatment of Chronic Pain
Steven J McKerrall, Teresa Nguyen, Kwong Wah Lai, et al.
Science (New York, N.Y.)
|
December 19, 2015
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist
Shivani Ahuja, Susmith Mukund, Lunbin Deng, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2024
Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na<sub>V</sub>1.7
Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, et al.
Journal of Medicinal Chemistry
|
May 9, 2018
Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa<sub>V</sub>1.7 Inhibitors for the Treatment of Pain
Thilo Focken, Sultan Chowdhury, Alla Zenova, et al.
Elife
|
March 2, 2022
NBI-921352, a first-in-class, Na<sub>V</sub>1.6 selective, sodium channel inhibitor that prevents seizures in <i>Scn8a</i> gain-of-function mice, and wild-type mice and rats
J P Johnson, Thilo Focken, Kuldip Khakh, et al.
Journal of Medicinal Chemistry
|
March 8, 2021
Discovery of Acyl-sulfonamide Na<sub>v</sub>1.7 Inhibitors GDC-0276 and GDC-0310
Brian S Safina, Steven J McKerrall, Shaoyi Sun, et al.
Page
of 29