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Current Opinion in Chemical Biology|August 26, 2000
New advances in the discovery of thrombin and factor Xa inhibitorsJ P VaccaDrug Metabolism and Disposition: the Biological Fate of Chemicals|December 22, 2000
P450 interaction with HIV protease inhibitors: relationship between metabolic stability, inhibitory potency, and P450 binding spectraM Chiba, L Jin, W Neway, et al.The Journal of Biological Chemistry|August 25, 1988
Metabolism of synthetic inositol trisphosphate analogsM A Polokoff, G H Bencen, J P Vacca, et al.Naunyn-Schmiedeberg'S Archives of Pharmacology|July 1, 1988
[3H]L-654,284 as a probe of the central alpha 2 adrenoceptorW C Randall, J R Huff, J P Vacca, et al.Biochemical Pharmacology|August 11, 1998
Metabolite-P450 complex formation by methylenedioxyphenyl HIV protease inhibitors in rat and human liver microsomesM Chiba, J A Nishime, I W Chen, et al.Journal of Medicinal Chemistry|April 17, 1998
Design of novel, potent, noncovalent inhibitors of thrombin with nonbasic P-1 substructures: rapid structure-activity studies by solid-phase synthesisW C Lumma, K M Witherup, T J Tucker, et al.Proceedings of the National Academy of Sciences of the United States of America|April 26, 1994
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitorJ P Vacca, B D Dorsey, W A Schleif, et al.Bioorganic & Medicinal Chemistry|September 1, 1994
Synthesis, antiviral activity, and bioavailability studies of gamma-lactam derived HIV protease inhibitorsR W Hungate, J L Chen, K E Starbuck, et al.Journal of Medicinal Chemistry|September 1, 1991
Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679S J deSolms, E A Giuliani, J P Guare, et al.Journal of Medicinal Chemistry|October 14, 1994
L-735,524: the design of a potent and orally bioavailable HIV protease inhibitorB D Dorsey, R B Levin, S L McDaniel, et al.Pageof 3