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European Journal of Medicinal Chemistry
|
May 17, 2003
The design of potent, non-peptidic inhibitors of hepatitis C protease
David M Andrews, Helene M Chaignot, Barry A Coomber, et al.
Organic Letters
|
November 25, 2003
Pyrrolidine-5,5-trans-lactams. 5. Pharmacokinetic optimization of inhibitors of hepatitis C virus NS3/4A protease
David M Andrews, Michael C Barnes, Mike D Dowle, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2007
Selective and dual action orally active inhibitors of thrombin and factor Xa
Robert J Young, David Brown, Cynthia L Burns-Kurtis, et al.
Journal of Cardiovascular Pharmacology
|
July 23, 2008
Antithrombotic potential of GW813893: a novel, orally active, active-site directed factor Xa inhibitor
Melanie A Abboud, Saul J Needle, Cynthia L Burns-Kurtis, et al.
Journal of Medicinal Chemistry
|
March 7, 2007
Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides
Chuen Chan, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2006
Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs
Robert J Young, Matthew Campbell, Alan D Borthwick, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 26, 2011
The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs
Nigel S Watson, Carl Adams, David Belton, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 26, 2011
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs
Robert J Young, Carl Adams, Mike Blows, et al.
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Search research articles
Search
Showing results (11-20 of 21) with videos related to
Sort By:
Page
of 3
European Journal of Medicinal Chemistry
|
May 17, 2003
The design of potent, non-peptidic inhibitors of hepatitis C protease
David M Andrews, Helene M Chaignot, Barry A Coomber, et al.
Organic Letters
|
November 25, 2003
Pyrrolidine-5,5-trans-lactams. 5. Pharmacokinetic optimization of inhibitors of hepatitis C virus NS3/4A protease
David M Andrews, Michael C Barnes, Mike D Dowle, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2007
Selective and dual action orally active inhibitors of thrombin and factor Xa
Robert J Young, David Brown, Cynthia L Burns-Kurtis, et al.
Journal of Cardiovascular Pharmacology
|
July 23, 2008
Antithrombotic potential of GW813893: a novel, orally active, active-site directed factor Xa inhibitor
Melanie A Abboud, Saul J Needle, Cynthia L Burns-Kurtis, et al.
Journal of Medicinal Chemistry
|
March 7, 2007
Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides
Chuen Chan, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2006
Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs
Robert J Young, Matthew Campbell, Alan D Borthwick, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 26, 2011
The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs
Nigel S Watson, Carl Adams, David Belton, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 26, 2011
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs
Robert J Young, Carl Adams, Mike Blows, et al.
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of 3