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Pain|March 16, 2011
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulationJun Chen, Shailen K Joshi, Stanley DiDomenico, et al.Journal of Medicinal Chemistry|February 4, 2005
Novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain: structure-activity relationships for ureas with quinoline, isoquinoline, quinazoline, phthalazine, quinoxaline, and cinnoline moietiesArthur Gomtsyan, Erol K Bayburt, Robert G Schmidt, et al.Bioorganic & Medicinal Chemistry|April 20, 2006
Structure-activity studies of a novel series of 5,6-fused heteroaromatic ureas as TRPV1 antagonistsIrene Drizin, Arthur Gomtsyan, Erol K Bayburt, et al.Journal of Medicinal Chemistry|August 8, 2014
Discovery of (R)-1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): a temperature-neutral transient receptor potential vanilloid-1 (TRPV1) antagonist with analgesic efficacyEric A Voight, Arthur R Gomtsyan, Jerome F Daanen, et al.Pageof 4