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Journal of Medicinal Chemistry|October 24, 2013
Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approachAndreas O Frank, Michael D Feldkamp, J Phillip Kennedy, et al.ACS Medicinal Chemistry Letters|February 21, 2015
Diphenylpyrazoles as replication protein a inhibitorsAlex G Waterson, J Phillip Kennedy, James D Patrone, et al.ACS Medicinal Chemistry Letters|September 28, 2018
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RASJason R Abbott, Pratiq A Patel, Jennifer E Howes, et al.Cancer Research|May 14, 2009
Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancerTodd W Miller, Marianela Pérez-Torres, Archana Narasanna, et al.Bioorganic & Medicinal Chemistry Letters|September 23, 2008
Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moietiesThomas M Bridges, Ashley E Brady, J Phillip Kennedy, et al.Bioorganic & Medicinal Chemistry Letters|January 8, 2008
Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonistsL Michelle Lewis, Douglas Sheffler, Richard Williams, et al.The Journal of Pharmacology and Experimental Therapeutics|September 6, 2008
Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in ratsAshley E Brady, Carrie K Jones, Thomas M Bridges, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 26, 2009
Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cellsTodd W Miller, James T Forbes, Chirayu Shah, et al.ACS Chemical Neuroscience|October 1, 2011
Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous systemEvan P Lebois, Thomas M Bridges, L Michelle Lewis, et al.Journal of Medicinal Chemistry|June 2, 2018
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS SignalingJason R Abbott, Timothy R Hodges, R Nathan Daniels, et al.Pageof 3