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J R McCarthy

Showing results (21-30 of 33) with videos related to

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Journal of Medicinal Chemistry|October 25, 1996
Rapid microscale synthesis, a new method for lead optimization using robotics and solution phase chemistry: application to the synthesis and optimization of corticotropin-releasing factor1 receptor antagonistsJ P Whitten, Y F Xie, P E Erickson, et al.
Journal of Medicinal Chemistry|September 18, 1992
N-(1-oxododecyl)-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol: a potent competitive inhibitor of 2,3-oxidosqualene cyclaseM W Wannamaker, P P Waid, W A Van Sickle, et al.
Journal of Medicinal Chemistry|March 1, 1986
Unsaturated heterocyclic amines as potent time-dependent inhibitors of dopamine beta-hydroxylaseT M Bargar, R J Broersma, L C Creemer, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 1, 1993
An alternative mechanism for the inhibition of cholesterol biosynthesis in HepG2 cells by N-[(1,5,9)-trimethyldecyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol (MDL 28,815)W A Van Sickle, P K Wilson, M W Wannamaker, et al.
Journal of Medicinal Chemistry|February 1, 1991
4',5'-unsaturated 5'-halogenated nucleosides. Mechanism-based and competitive inhibitors of S-adenosyl-L-homocysteine hydrolaseE T Jarvi, J R McCarthy, S Mehdi, et al.
Biochemistry|June 25, 1996
Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitorsW A van der Donk, G Yu, D J Silva, et al.
Journal of Medicinal Chemistry|July 1, 1990
1-(Thienylalkyl)imidazole-2(3H)-thiones as potent competitive inhibitors of dopamine beta-hydroxylaseJ R McCarthy, D P Matthews, R J Broersma, et al.
Journal of Medicinal Chemistry|January 1, 1990
Synthesis and cardiotonic activity of novel biimidazolesD P Matthews, J R McCarthy, J P Whitten, et al.
Cancer Research|March 15, 1994
Regression of human breast tumor xenografts in response to (E)-2'-deoxy-2'-(fluoromethylene)cytidine, an inhibitor of ribonucleoside diphosphate reductaseA J Bitonti, J A Dumont, T L Bush, et al.
Journal of Medicinal Chemistry|September 1, 1985
6,7-Dihydro-5-[[(cis-2-hydroxy-trans-3-phenoxycyclopentyl)amino] methyl]-2-methylbenzo[b]thiophen-4(5H)-one: a novel alpha 1-adrenergic receptor antagonist and renal vasodilatorJ R McCarthy, M B Zimmerman, D L Trepanier, et al.
Pageof 4

Showing results (21-30 of 33) with videos related to

Sort By:
Pageof 4
Journal of Medicinal Chemistry|October 25, 1996
Rapid microscale synthesis, a new method for lead optimization using robotics and solution phase chemistry: application to the synthesis and optimization of corticotropin-releasing factor1 receptor antagonistsJ P Whitten, Y F Xie, P E Erickson, et al.
Journal of Medicinal Chemistry|September 18, 1992
N-(1-oxododecyl)-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol: a potent competitive inhibitor of 2,3-oxidosqualene cyclaseM W Wannamaker, P P Waid, W A Van Sickle, et al.
Journal of Medicinal Chemistry|March 1, 1986
Unsaturated heterocyclic amines as potent time-dependent inhibitors of dopamine beta-hydroxylaseT M Bargar, R J Broersma, L C Creemer, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 1, 1993
An alternative mechanism for the inhibition of cholesterol biosynthesis in HepG2 cells by N-[(1,5,9)-trimethyldecyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol (MDL 28,815)W A Van Sickle, P K Wilson, M W Wannamaker, et al.
Journal of Medicinal Chemistry|February 1, 1991
4',5'-unsaturated 5'-halogenated nucleosides. Mechanism-based and competitive inhibitors of S-adenosyl-L-homocysteine hydrolaseE T Jarvi, J R McCarthy, S Mehdi, et al.
Biochemistry|June 25, 1996
Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitorsW A van der Donk, G Yu, D J Silva, et al.
Journal of Medicinal Chemistry|July 1, 1990
1-(Thienylalkyl)imidazole-2(3H)-thiones as potent competitive inhibitors of dopamine beta-hydroxylaseJ R McCarthy, D P Matthews, R J Broersma, et al.
Journal of Medicinal Chemistry|January 1, 1990
Synthesis and cardiotonic activity of novel biimidazolesD P Matthews, J R McCarthy, J P Whitten, et al.
Cancer Research|March 15, 1994
Regression of human breast tumor xenografts in response to (E)-2'-deoxy-2'-(fluoromethylene)cytidine, an inhibitor of ribonucleoside diphosphate reductaseA J Bitonti, J A Dumont, T L Bush, et al.
Journal of Medicinal Chemistry|September 1, 1985
6,7-Dihydro-5-[[(cis-2-hydroxy-trans-3-phenoxycyclopentyl)amino] methyl]-2-methylbenzo[b]thiophen-4(5H)-one: a novel alpha 1-adrenergic receptor antagonist and renal vasodilatorJ R McCarthy, M B Zimmerman, D L Trepanier, et al.
Pageof 4