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The Journal of Clinical Investigation|May 20, 2009
Antagonism of T-type calcium channels inhibits high-fat diet-induced weight gain in miceVictor N Uebele, Anthony L Gotter, Cindy E Nuss, et al.Bioorganic & Medicinal Chemistry Letters|November 13, 2013
Discovery of 2,5-diarylnicotinamides as selective orexin-2 receptor antagonists (2-SORAs)Swati P Mercer, Anthony J Roecker, Susan Garson, et al.Bioorganic & Medicinal Chemistry Letters|January 24, 2015
Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacementsAnthony J Roecker, Swati P Mercer, Jeffrey M Bergman, et al.Brain Research|September 3, 2011
TASK-3 as a potential antidepressant targetAnthony L Gotter, Vincent P Santarelli, Scott M Doran, et al.Bioorganic & Medicinal Chemistry Letters|January 22, 2008
Proline bis-amides as potent dual orexin receptor antagonistsJeffrey M Bergman, Anthony J Roecker, Swati P Mercer, et al.Bioorganic & Medicinal Chemistry Letters|May 19, 2015
Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development propertiesScott D Kuduk, Jason W Skudlarek, Christina N DiMarco, et al.Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|June 1, 2013
Quantitative electroencephalography within sleep/wake states differentiates GABAA modulators eszopiclone and zolpidem from dual orexin receptor antagonists in ratsSteven V Fox, Anthony L Gotter, Spencer J Tye, et al.Bioorganic & Medicinal Chemistry Letters|June 1, 2010
Synthesis and evaluation of a new series of Neuropeptide S receptor antagonistsJeffrey Y Melamed, Amy E Zartman, Nathan R Kett, et al.Chemmedchem|September 15, 2011
Discovery of a pharmacologically active antagonist of the two-pore-domain potassium channel K2P9.1 (TASK-3)Craig A Coburn, Yunfu Luo, Mingxiang Cui, et al.BMC Neuroscience|August 29, 2013
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy thresholdAnthony L Gotter, Christopher J Winrow, Joseph Brunner, et al.Pageof 13