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Bioorganic & Medicinal Chemistry Letters|November 8, 2016
Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacologyCraig A Stump, Andrew J Cooke, Joseph Bruno, et al.International Journal of Molecular Sciences|August 26, 2023
A Comparative Study on the Lysosomal Cation Channel TMEM175 Using Automated Whole-Cell Patch-Clamp, Lysosomal Patch-Clamp, and Solid Supported Membrane-Based Electrophysiology: Functional Characterization and High-Throughput Screening Assay DevelopmentAndre Bazzone, Maria Barthmes, Cecilia George, et al.Neuropharmacology|November 30, 2010
T-type calcium channel antagonism produces antipsychotic-like effects and reduces stimulant-induced glutamate release in the nucleus accumbens of ratsJason M Uslaner, Sean M Smith, Sarah L Huszar, et al.Frontiers in Behavioral Neuroscience|June 7, 2014
Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogsPamela L Tannenbaum, Joanne Stevens, Jacquelyn Binns, et al.Diabetes|October 9, 2013
Genetic deletion and pharmacological inhibition of phosphodiesterase 10A protects mice from diet-induced obesity and insulin resistanceAndrea R Nawrocki, Carlos G Rodriguez, Dawn M Toolan, et al.BMC Neuroscience|September 23, 2014
Differential sleep-promoting effects of dual orexin receptor antagonists and GABAA receptor modulatorsAnthony L Gotter, Susan L Garson, Joanne Stevens, et al.Neuroreport|February 13, 2009
T-type calcium channels regulate cortical plasticity in-vivo. [corrected]Victor N Uebele, Cindy E Nuss, Vincent P Santarelli, et al.Journal of Neurogenetics|April 9, 2011
Promotion of sleep by suvorexant-a novel dual orexin receptor antagonistChristopher J Winrow, Anthony L Gotter, Christopher D Cox, et al.Bioorganic & Medicinal Chemistry Letters|March 18, 2014
Synthesis and evaluation of carbon-linked analogs of dual orexin receptor antagonist filorexantScott D Kuduk, Jason W Skudlarek, Christina N Di Marco, et al.Neuropharmacology|July 4, 2012
The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkeySean M Smith, Jason M Uslaner, Christopher D Cox, et al.Pageof 13