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Chemical Biology & Drug Design|May 22, 2010
The use of biochemical and biophysical tools for triage of high-throughput screening hits - A case study with Escherichia coli phosphopantetheine adenylyltransferaseJ Richard Miller, Venkataraman Thanabal, Michael M Melnick, et al.
Journal of Medicinal Chemistry|January 17, 2012
Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generationJun Yong Choi, Mark S Plummer, Jeremy Starr, et al.
ACS Chemical Biology|May 6, 2009
Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approachesIgor Mochalkin, J Richard Miller, Lakshmi Narasimhan, et al.
Bioorganic & Medicinal Chemistry Letters|February 23, 2023
Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methodsSymon Gathiaka, Rachel L Palte, Sung-Sau So, et al.
ACS Medicinal Chemistry Letters|March 19, 2021
Identification of Potent Reverse Indazole Inhibitors for HPK1Elsie C Yu, Joey L Methot, Xavier Fradera, et al.
Bioorganic & Medicinal Chemistry Letters|August 15, 2021
Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffoldWensheng Yu, Yongqi Deng, David Sloman, et al.
Toxicology and Applied Pharmacology|September 2, 2020
Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout miceAmy G Aslamkhan, Qiuwei Xu, Amy Loughlin, et al.
Cancer Immunology Research|February 21, 2020
Cancer-Associated Fibroblasts Promote Immunosuppression by Inducing ROS-Generating Monocytic MDSCs in Lung Squamous Cell CarcinomaHandan Xiang, Carlo P Ramil, Josephine Hai, et al.
The Journal of Experimental Medicine|June 15, 2019
Mg2+ regulation of kinase signaling and immune functionChryssa Kanellopoulou, Alex B George, Evan Masutani, et al.
ACS Medicinal Chemistry Letters|September 17, 2021
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 InhibitorsBrett Hopkins, Hongjun Zhang, Indu Bharathan, et al.
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