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Journal of Medicinal Chemistry|March 2, 2018
Covalent Allosteric Probe for the Metabotropic Glutamate Receptor 2: Design, Synthesis, and Pharmacological CharacterizationMaarten L J Doornbos, Xuesong Wang, Sophie C Vermond, et al.Science (New York, N.Y.)|July 17, 2012
Structural basis for allosteric regulation of GPCRs by sodium ionsWei Liu, Eugene Chun, Aaron A Thompson, et al.Biochemical Pharmacology|April 8, 2022
Kinetic profiling and functional characterization of 8-phenylxanthine derivatives as A2B adenosine receptor antagonistsAnna Vlachodimou, Henk de Vries, Milena Pasoli, et al.Molecular Pharmacology|July 16, 2014
Discovery and mapping of an intracellular antagonist binding site at the chemokine receptor CCR2Annelien J M Zweemer, Julia Bunnik, Margo Veenhuizen, et al.Journal of Medicinal Chemistry|May 9, 2012
A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library designMarijn P A Sanders, Luc Roumen, Eelke van der Horst, et al.Journal of Medicinal Chemistry|May 16, 2014
Structure-activity relationships of privileged structures lead to the discovery of novel biased ligands at the dopamine D₂ receptorMonika Szabo, Carmen Klein Herenbrink, Arthur Christopoulos, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|November 19, 2015
The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasionCindy K Pon, J Robert Lane, Erica K Sloan, et al.Biochemical Pharmacology|August 12, 2009
The endocannabinoid 2-arachidonylglycerol is a negative allosteric modulator of the human A3 adenosine receptorJ Robert Lane, Margot W Beukers, Thea Mulder-Krieger, et al.Journal of Medicinal Chemistry|March 18, 2005
A series of ligands displaying a remarkable agonistic-antagonistic profile at the adenosine A1 receptorLisa C W Chang, Jacobien K von Frijtag Drabbe Künzel, Thea Mulder-Krieger, et al.Scientific Reports|November 12, 2017
Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter NTCPJoanne M Donkers, Benno Zehnder, Gerard J P van Westen, et al.Pageof 33