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Frontiers in Pharmacology|June 9, 2022
Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate TransportersHubert J Sijben, Laura Dall' Acqua, Rongfang Liu, et al.Journal of Chemical Information and Modeling|April 29, 2020
Successive Statistical and Structure-Based Modeling to Identify Chemically Novel Kinase InhibitorsLindsey Burggraaff, Eelke B Lenselink, Willem Jespers, et al.Medicinal Research Reviews|May 7, 2014
Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspectiveJeremy Shonberg, Laura Lopez, Peter J Scammells, et al.Nature Chemical Biology|August 19, 2017
A kinetic view of GPCR allostery and biased agonismJ Robert Lane, Lauren T May, Robert G Parton, et al.Journal of Medicinal Chemistry|January 16, 2015
Proof of concept study for designed multiple ligands targeting the dopamine D2, serotonin 5-HT2A, and muscarinic M1 acetylcholine receptorsMonika Szabo, Herman D Lim, Carmen Klein Herenbrink, et al.Molecular Pharmacology|May 28, 2015
Biased Agonism of Endogenous Opioid Peptides at the μ-Opioid ReceptorGeorgina L Thompson, J Robert Lane, Thomas Coudrat, et al.Biochemical Pharmacology|June 12, 2016
Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptorGeorgina L Thompson, J Robert Lane, Thomas Coudrat, et al.Arteriosclerosis, Thrombosis, and Vascular Biology|June 30, 2012
Adenosine A₂B receptor agonism inhibits neointimal lesion development after arterial injury in apolipoprotein E-deficient miceIlze Bot, Henk de Vries, Suzanne J A Korporaal, et al.Journal of Medicinal Chemistry|September 3, 2014
Synthesis and biological evaluation of novel allosteric enhancers of the A1 adenosine receptor based on 2-amino-3-(4'-chlorobenzoyl)-4-substituted-5-arylethynyl thiopheneRomeo Romagnoli, Pier Giovanni Baraldi, Adriaan P IJzerman, et al.The Journal of Biological Chemistry|November 17, 2011
A Monod-Wyman-Changeux mechanism can explain G protein-coupled receptor (GPCR) allosteric modulationMeritxell Canals, J Robert Lane, Adriel Wen, et al.Pageof 33