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International Journal of Molecular Sciences|April 30, 2021
Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10Herman D Lim, J Robert Lane, Meritxell Canals, et al.Molecular Pharmacology|February 9, 2007
Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3J Robert Lane, Ben Powney, Alan Wise, et al.Molecules (Basel, Switzerland)|July 2, 2021
Enantioenriched Positive Allosteric Modulators Display Distinct Pharmacology at the Dopamine D1 ReceptorTim J Fyfe, Peter J Scammells, J Robert Lane, et al.Journal of Medicinal Chemistry|May 16, 2014
Structure-activity relationships of privileged structures lead to the discovery of novel biased ligands at the dopamine D₂ receptorMonika Szabo, Carmen Klein Herenbrink, Arthur Christopoulos, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|November 19, 2015
The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasionCindy K Pon, J Robert Lane, Erica K Sloan, et al.Biochemical Pharmacology|August 12, 2009
The endocannabinoid 2-arachidonylglycerol is a negative allosteric modulator of the human A3 adenosine receptorJ Robert Lane, Margot W Beukers, Thea Mulder-Krieger, et al.Journal of Medicinal Chemistry|January 17, 2012
Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluationFiona M McRobb, Ian T Crosby, Elizabeth Yuriev, et al.British Journal of Pharmacology|March 17, 2022
The respiratory depressant effects of mitragynine are limited by its conversion to 7-OH mitragynineRob Hill, Andrew C Kruegel, Jonathan A Javitch, et al.Molecular Pharmacology|December 1, 2012
Allosteric modulation of a chemogenetically modified G protein-coupled receptorAlaa Abdul-Ridha, J Robert Lane, Patrick M Sexton, et al.Medicinal Research Reviews|May 7, 2014
Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspectiveJeremy Shonberg, Laura Lopez, Peter J Scammells, et al.Pageof 10