Showing results (21-30 of 92) with videos related to
Sort By:
Pageof 10
Journal of Medicinal Chemistry|March 30, 2010
Hybrid ortho/allosteric ligands for the adenosine A(1) receptorRajeshwar Narlawar, J Robert Lane, Munikumar Doddareddy, et al.Nature Chemical Biology|August 19, 2017
A kinetic view of GPCR allostery and biased agonismJ Robert Lane, Lauren T May, Robert G Parton, et al.Journal of Medicinal Chemistry|January 16, 2015
Proof of concept study for designed multiple ligands targeting the dopamine D2, serotonin 5-HT2A, and muscarinic M1 acetylcholine receptorsMonika Szabo, Herman D Lim, Carmen Klein Herenbrink, et al.Molecular Pharmacology|May 28, 2015
Biased Agonism of Endogenous Opioid Peptides at the μ-Opioid ReceptorGeorgina L Thompson, J Robert Lane, Thomas Coudrat, et al.Biochemical Pharmacology|June 12, 2016
Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptorGeorgina L Thompson, J Robert Lane, Thomas Coudrat, et al.The Journal of Biological Chemistry|November 17, 2011
A Monod-Wyman-Changeux mechanism can explain G protein-coupled receptor (GPCR) allosteric modulationMeritxell Canals, J Robert Lane, Adriel Wen, et al.Biochemical Pharmacology|July 6, 2010
Characterization of [3H]LUF5834: A novel non-ribose high-affinity agonist radioligand for the adenosine A1 receptorJ Robert Lane, Elisabeth Klaasse, Judy Lin, et al.European Journal of Medicinal Chemistry|March 9, 2019
Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D2 receptorTim J Fyfe, Barrie Kellam, Shailesh N Mistry, et al.ACS Chemical Neuroscience|February 19, 2016
Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcholine ReceptorShailesh N Mistry, Herman Lim, Manuela Jörg, et al.Journal of Medicinal Chemistry|October 22, 2013
A structure-activity analysis of biased agonism at the dopamine D2 receptorJeremy Shonberg, Carmen Klein Herenbrink, Laura López, et al.Pageof 10