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Diseases (Basel, Switzerland)
|
June 26, 2024
Differential Inflammatory Cytokine Elaboration in Serum from Brick Kiln Workers in Bhaktapur, Nepal
Katrina L Curtis, Ashley Chang, James D Johnston, et al.
Nature Medicine
|
August 29, 2017
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates
Shannon E Mullican, Xiefan Lin-Schmidt, Chen-Ni Chin, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 31, 2007
Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein
Christopher D Cox, Michael J Breslin, David B Whitman, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2007
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP
Anthony J Roecker, Paul J Coleman, Swati P Mercer, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2006
Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP
Christopher D Cox, Maricel Torrent, Michael J Breslin, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 28, 2006
Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP
Mark E Fraley, Robert M Garbaccio, Kenneth L Arrington, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 1, 2007
Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP
Paul J Coleman, John D Schreier, Christopher D Cox, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 28, 2006
Kinesin spindle protein (KSP) inhibitors. Part 3: synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility
Robert M Garbaccio, Mark E Fraley, Edward S Tasber, et al.
Journal of Medicinal Chemistry
|
June 27, 2008
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer
Christopher D Cox, Paul J Coleman, Michael J Breslin, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 7, 2007
Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP
Robert M Garbaccio, Edward S Tasber, Lou Anne Neilson, et al.
Page
of 11
Search research articles
Search
Showing results (101-110 of 110) with videos related to
Sort By:
Page
of 11
You have reached the last page of results.
This site can display upto 110 results.
Diseases (Basel, Switzerland)
|
June 26, 2024
Differential Inflammatory Cytokine Elaboration in Serum from Brick Kiln Workers in Bhaktapur, Nepal
Katrina L Curtis, Ashley Chang, James D Johnston, et al.
Nature Medicine
|
August 29, 2017
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates
Shannon E Mullican, Xiefan Lin-Schmidt, Chen-Ni Chin, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 31, 2007
Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein
Christopher D Cox, Michael J Breslin, David B Whitman, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2007
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP
Anthony J Roecker, Paul J Coleman, Swati P Mercer, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2006
Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP
Christopher D Cox, Maricel Torrent, Michael J Breslin, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 28, 2006
Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP
Mark E Fraley, Robert M Garbaccio, Kenneth L Arrington, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 1, 2007
Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP
Paul J Coleman, John D Schreier, Christopher D Cox, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 28, 2006
Kinesin spindle protein (KSP) inhibitors. Part 3: synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility
Robert M Garbaccio, Mark E Fraley, Edward S Tasber, et al.
Journal of Medicinal Chemistry
|
June 27, 2008
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer
Christopher D Cox, Paul J Coleman, Michael J Breslin, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 7, 2007
Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP
Robert M Garbaccio, Edward S Tasber, Lou Anne Neilson, et al.
Page
of 11