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J Scott Daniels

Showing results (51-60 of 122) with videos related to

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Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 6, 2005
Evaluation of microdosing to assess pharmacokinetic linearity in rats using liquid chromatography-tandem mass spectrometrySuresh K Balani, Nelamangala V Nagaraja, Mark G Qian, et al.
Bioorganic & Medicinal Chemistry Letters|February 19, 2013
Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: the continued optimization of an MLPCN probe moleculeMichael S Poslusney, Bruce J Melancon, Patrick R Gentry, et al.
Bioorganic & Medicinal Chemistry Letters|August 13, 2013
Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu1Jason T Manka, Alice L Rodriguez, Ryan D Morrison, et al.
ACS Chemical Neuroscience|November 27, 2018
Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain ModelsKristopher K Abney, Michael Bubser, Yu Du, et al.
ACS Chemical Biology|May 28, 2011
Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133Hao-Ran Wang, Meng Wu, Haibo Yu, et al.
BMC Pharmacology & Toxicology|January 7, 2019
First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteersLisa M Pitchford, John A Rathmacher, John C Fuller, et al.
ACS Chemical Neuroscience|May 21, 2013
Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addictionRussell J Amato, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters|November 18, 2018
Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5Andrew S Felts, Katrina A Bollinger, Christopher J Brassard, et al.
Bioorganic & Medicinal Chemistry Letters|June 4, 2013
N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in ratsKimberly M Lovell, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters|May 29, 2016
Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Rocco D Gogliotti, Anna L Blobaum, Ryan M Morrison, et al.
Pageof 13

Showing results (51-60 of 122) with videos related to

Sort By:
Pageof 13
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 6, 2005
Evaluation of microdosing to assess pharmacokinetic linearity in rats using liquid chromatography-tandem mass spectrometrySuresh K Balani, Nelamangala V Nagaraja, Mark G Qian, et al.
Bioorganic & Medicinal Chemistry Letters|February 19, 2013
Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: the continued optimization of an MLPCN probe moleculeMichael S Poslusney, Bruce J Melancon, Patrick R Gentry, et al.
Bioorganic & Medicinal Chemistry Letters|August 13, 2013
Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu1Jason T Manka, Alice L Rodriguez, Ryan D Morrison, et al.
ACS Chemical Neuroscience|November 27, 2018
Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain ModelsKristopher K Abney, Michael Bubser, Yu Du, et al.
ACS Chemical Biology|May 28, 2011
Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133Hao-Ran Wang, Meng Wu, Haibo Yu, et al.
BMC Pharmacology & Toxicology|January 7, 2019
First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteersLisa M Pitchford, John A Rathmacher, John C Fuller, et al.
ACS Chemical Neuroscience|May 21, 2013
Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addictionRussell J Amato, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters|November 18, 2018
Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5Andrew S Felts, Katrina A Bollinger, Christopher J Brassard, et al.
Bioorganic & Medicinal Chemistry Letters|June 4, 2013
N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in ratsKimberly M Lovell, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters|May 29, 2016
Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Rocco D Gogliotti, Anna L Blobaum, Ryan M Morrison, et al.
Pageof 13