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J Spurlino

Showing results (1-10 of 9) with videos related to

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Structure (London, England : 1993)|March 15, 1997
Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discoveryF R Salemme, J Spurlino, R Bone
Proceedings of the National Academy of Sciences of the United States of America|August 1, 1990
Acetylcholine receptor-alpha-bungarotoxin interactions: determination of the region-to-region contacts by peptide-peptide interactions and molecular modeling of the receptor cavityK H Ruan, J Spurlino, F A Quiocho, et al.
Journal of Protein Chemistry|December 11, 1992
Method for calculating 3-D coordinates from molecular stereogramsJ Guevara, R D Knapp, J Spurlino, et al.
Bioorganic & Medicinal Chemistry Letters|January 5, 1999
In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitorsT Lu, B Tomczuk, C R Illig, et al.
Biophysical Journal|March 1, 1993
Proposed mechanisms for binding of apo[a] kringle type 9 to apo B-100 in human lipoprotein[a]J Guevara, J Spurlino, A Y Jan, et al.
Bioorganic & Medicinal Chemistry Letters|January 15, 2000
Structure-activity and crystallographic analysis of a new class of non-amide-based thrombin inhibitorT Lu, R M Soll, C R Illig, et al.
Bioorganic & Medicinal Chemistry Letters|January 15, 2000
Amidinohydrazones as guanidine bioisosteres: application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitorsR M Soll, T Lu, B Tomczuk, et al.
Bioorganic & Medicinal Chemistry Letters|April 11, 2001
Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitorsK J Wilson, C R Illig, N Subasinghe, et al.
Bioorganic & Medicinal Chemistry Letters|May 30, 2001
Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitorsN L Subasinghe, C Illig, J Hoffman, et al.
Pageof 1

Showing results (1-10 of 9) with videos related to

Sort By:
Pageof 1
Structure (London, England : 1993)|March 15, 1997
Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discoveryF R Salemme, J Spurlino, R Bone
Proceedings of the National Academy of Sciences of the United States of America|August 1, 1990
Acetylcholine receptor-alpha-bungarotoxin interactions: determination of the region-to-region contacts by peptide-peptide interactions and molecular modeling of the receptor cavityK H Ruan, J Spurlino, F A Quiocho, et al.
Journal of Protein Chemistry|December 11, 1992
Method for calculating 3-D coordinates from molecular stereogramsJ Guevara, R D Knapp, J Spurlino, et al.
Bioorganic & Medicinal Chemistry Letters|January 5, 1999
In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitorsT Lu, B Tomczuk, C R Illig, et al.
Biophysical Journal|March 1, 1993
Proposed mechanisms for binding of apo[a] kringle type 9 to apo B-100 in human lipoprotein[a]J Guevara, J Spurlino, A Y Jan, et al.
Bioorganic & Medicinal Chemistry Letters|January 15, 2000
Structure-activity and crystallographic analysis of a new class of non-amide-based thrombin inhibitorT Lu, R M Soll, C R Illig, et al.
Bioorganic & Medicinal Chemistry Letters|January 15, 2000
Amidinohydrazones as guanidine bioisosteres: application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitorsR M Soll, T Lu, B Tomczuk, et al.
Bioorganic & Medicinal Chemistry Letters|April 11, 2001
Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitorsK J Wilson, C R Illig, N Subasinghe, et al.
Bioorganic & Medicinal Chemistry Letters|May 30, 2001
Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitorsN L Subasinghe, C Illig, J Hoffman, et al.
Pageof 1