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Journal of Medicinal Chemistry|March 4, 2016
Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment ScreeningJennifer A Borthwick, Nicolas Ancellin, Sophie M Bertrand, et al.Journal of Medicinal Chemistry|September 15, 2018
Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic αPanayiotis A Procopiou, Niall A Anderson, John Barrett, et al.Translational Psychiatry|March 8, 2017
Effects of naltrexone are influenced by childhood adversity during negative emotional processing in addiction recoveryG Savulich, R Riccelli, L Passamonti, et al.Journal of Medicinal Chemistry|July 25, 2017
Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related BiomarkersNahoum G Anthony, Jessica Baiget, Giacomo Berretta, et al.Nature Communications|November 23, 2024
Viral sequence determines HLA-E-restricted T cell recognition of hepatitis B surface antigenGavuthami Murugesan, Rachel L Paterson, Rakesh Kulkarni, et al.Journal of Medicinal Chemistry|January 16, 2016
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one DerivativesSusan M Westaway, Alex G S Preston, Michael D Barker, et al.Journal of Medicinal Chemistry|August 13, 2021
Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical ProgressionKatherine L Jones, Dominic M Beaumont, Sharon G Bernard, et al.Hepatology (Baltimore, Md.)|August 10, 2020
Immune-Mobilizing Monoclonal T Cell Receptors Mediate Specific and Rapid Elimination of Hepatitis B-Infected CellsJoannah R Fergusson, Zoë Wallace, Mary M Connolly, et al.The Journal of Experimental Medicine|June 29, 2023
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responsesAndrew Chancellor, Robert Alan Simmons, Rahul C Khanolkar, et al.Journal of Medicinal Chemistry|June 20, 2015
The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS HitsSophie M Bertrand, Nicolas Ancellin, Benjamin Beaufils, et al.Pageof 23