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Bioorganic & Medicinal Chemistry Letters|March 18, 2003
Exploring new non-sugar sulfated molecules as activators of antithrombinGunnar T Gunnarsson, Umesh R DesaiThrombosis Research|September 23, 2014
Sulfated low molecular weight lignins, allosteric inhibitors of coagulation proteinases via the heparin binding site, significantly alter the active site of thrombin and factor xa compared to heparinBrian L Henry, Umesh R DesaiExpert Opinion on Drug Discovery|June 3, 2014
Discovery methodology for the development of direct factor VIIa inhibitorsBrian L Henry, Umesh R DesaiJournal of Medicinal Chemistry|September 20, 2002
Interaction of designed sulfated flavanoids with antithrombin: lessons on the design of organic activatorsGunnar T Gunnarsson, Umesh R DesaiJournal of Medicinal Chemistry|February 18, 2005
Antithrombin activation by nonsulfated, non-polysaccharide organic polymerBernhard H Monien, Umesh R DesaiBiomolecules|November 25, 2023
Assessing Genetic Algorithm-Based Docking Protocols for Prediction of Heparin Oligosaccharide Binding Geometries onto ProteinsSamuel G Holmes, Umesh R DesaiChemistry (Weinheim an Der Bergstrasse, Germany)|July 18, 2024
Synthesis and Reactivity of Masked Organic SulfatesBharath Kumar Villuri, Umesh R DesaiCardiovascular & Hematological Agents in Medicinal Chemistry|October 16, 2008
Recent research developments in the direct inhibition of coagulation proteinases--inhibitors of the initiation phaseBrian L Henry, Umesh R DesaiJournal of Medicinal Chemistry|March 8, 2002
Designing small, nonsugar activators of antithrombin using hydropathic interaction analysesGunnar T Gunnarsson, Umesh R DesaiBiochemical and Biophysical Research Communications|September 10, 2014
Substantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2Akul Y Mehta, Umesh R DesaiPageof 16