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Bioorganic & Medicinal Chemistry Letters|April 9, 2008
The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutationsThomas J Tucker, Sandeep Saggar, John T Sisko, et al.
Nature|June 6, 2020
A lower X-gate in TASK channels traps inhibitors within the vestibuleKarin E J Rödström, Aytuğ K Kiper, Wei Zhang, et al.
ACS Medicinal Chemistry Letters|January 8, 2019
Privileged Structures and Polypharmacology within and between Protein FamiliesJoshua Meyers, Nicola E A Chessum, Salyha Ali, et al.
Journal of Medicinal Chemistry|November 14, 1997
Synthesis of a series of potent and orally bioavailable thrombin inhibitors that utilize 3,3-disubstituted propionic acid derivatives in the P3 positionT J Tucker, W C Lumma, S D Lewis, et al.
JCI Insight|October 12, 2023
Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lungCarol S Trempus, Brian N Papas, Maria I Sifre, et al.
The American Journal of Tropical Medicine and Hygiene|August 5, 2010
Prediction, assessment of the Rift Valley fever activity in East and Southern Africa 2006-2008 and possible vector control strategiesAssaf Anyamba, Kenneth J Linthicum, Jennifer Small, et al.
Human Genetics|May 14, 2020
Genomic sequencing highlights the diverse molecular causes of Perrault syndrome: a peroxisomal disorder (PEX6), metabolic disorders (CLPP, GGPS1), and mtDNA maintenance/translation disorders (LARS2, TFAM)Elena J Tucker, Rocio Rius, Sylvie Jaillard, et al.
Genome Biology|June 24, 2008
Gene expression response in target organ and whole blood varies as a function of target organ injury phenotypeEdward K Lobenhofer, J Todd Auman, Pamela E Blackshear, et al.
Science (New York, N.Y.)|February 23, 2019
A pharmacological master key mechanism that unlocks the selectivity filter gate in K<sup>+</sup> channelsMarcus Schewe, Han Sun, Ümit Mert, et al.
Plos Genetics|January 4, 2014
Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expressionElena J Tucker, Bas F J Wanschers, Radek Szklarczyk, et al.
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