Showing results (501-510 of 513) with videos related to
Sort By:
Pageof 52
Journal of Cardiac Failure|December 21, 2021
The Effect of Spironolactone in Patients With Obesity at Risk for Heart Failure: Proteomic Insights from the HOMAGE TrialJob A J Verdonschot, JoÃo Pedro Ferreira, Anne Pizard, et al.Journal of Medicinal Chemistry|August 17, 2016
Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153)Robert H Bradbury, Rowena Callis, Gregory R Carr, et al.Journal of Medicinal Chemistry|August 13, 2013
Structure- and reactivity-based development of covalent inhibitors of the activating and gatekeeper mutant forms of the epidermal growth factor receptor (EGFR)Richard A Ward, Mark J Anderton, Susan Ashton, et al.Molecular Cancer Therapeutics|August 31, 2016
AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic MalignanciesGarrett W Rhyasen, Maureen M Hattersley, Yi Yao, et al.Nature Chemical Biology|October 25, 2016
Potent and selective bivalent inhibitors of BET bromodomainsMichael J Waring, Huawei Chen, Alfred A Rabow, et al.Journal of Medicinal Chemistry|April 25, 2022
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain InhibitorDuncan C Miller, Tristan Reuillon, Lauren Molyneux, et al.Journal of Medicinal Chemistry|May 10, 2017
Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic InhibitorsWilliam McCoull, Roman D Abrams, Erica Anderson, et al.ACS Chemical Biology|October 19, 2018
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6William McCoull, Tony Cheung, Erica Anderson, et al.Nature Communications|October 8, 2020
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main proteaseAlice Douangamath, Daren Fearon, Paul Gehrtz, et al.Journal of Medicinal Chemistry|July 2, 2021
An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing KinaseIslam Al-Khawaldeh, Mohammed J Al Yasiri, Gregory G Aldred, et al.Pageof 52