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Journal of Medicinal Chemistry|January 23, 2014
2,4-Diaminothienopyrimidines as orally active antimalarial agentsDiego González Cabrera, Claire Le Manach, Frederic Douelle, et al.Journal of Medicinal Chemistry|March 7, 2012
3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potentialYassir Younis, Frederic Douelle, Tzu-Shean Feng, et al.Journal of Medicinal Chemistry|October 27, 2015
A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial ImidazopyridazinesClaire Le Manach, Tanya Paquet, Christel Brunschwig, et al.Journal of Medicinal Chemistry|March 18, 2022
Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal TrypanosomiasisAlasdair Smith, Richard J Wall, Stephen Patterson, et al.Journal of Medicinal Chemistry|October 18, 2016
Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life CycleClaire Le Manach, Aloysius T Nchinda, Tanya Paquet, et al.Antimicrobial Agents and Chemotherapy|June 27, 2018
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of MalariaChristel Brunschwig, Nina Lawrence, Dale Taylor, et al.Science Translational Medicine|April 28, 2017
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinaseTanya Paquet, Claire Le Manach, Diego González Cabrera, et al.Pageof 3