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Chemical Research in Toxicology|July 18, 2006
Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cellsYun Fan, Emanuel M Schreiber, Angela Giorgianni, et al.
Bioorganic & Medicinal Chemistry|October 6, 2014
Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNAArun A Yadav, Xing Wu, Daywin Patel, et al.
Chemical Research in Toxicology|January 17, 2008
Thiol-modulated mechanisms of the cytotoxicity of thimerosal and inhibition of DNA topoisomerase II alphaXing Wu, Hong Liang, Kimberley A O'Hara, et al.
Bioorganic & Medicinal Chemistry|December 17, 2009
A diazirine-based photoaffinity etoposide probe for labeling topoisomerase IIGaik-Lean Chee, Jack C Yalowich, Andrew Bodner, et al.
Biochemical Pharmacology|April 17, 2012
The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIαJack C Yalowich, Xing Wu, Rui Zhang, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 15, 2015
Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα IsoformBrian B Hasinoff, Xing Wu, Daywin Patel, et al.
Cancers|July 9, 2022
Intronic Polyadenylation in Acquired Cancer Drug Resistance Circumvented by Utilizing CRISPR/Cas9 with Homology-Directed Repair: The Tale of Human DNA Topoisomerase IIαTerry S Elton, Victor A Hernandez, Jessika Carvajal-Moreno, et al.
Bioorganic & Medicinal Chemistry|April 30, 2015
Structure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogsArun A Yadav, Gaik-Lean Chee, Xing Wu, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 21, 2022
Effects of hsa-miR-9-3p and hsa-miR-9-5p on Topoisomerase IIβ Expression in Human Leukemia K562 Cells with Acquired Resistance to EtoposideJessika Carvajal-Moreno, Victor A Hernandez, Xinyi Wang, et al.
Plos One|May 26, 2022
Use of CRISPR/Cas9 with homology-directed repair to silence the human topoisomerase IIα intron-19 5' splice site: Generation of etoposide resistance in human leukemia K562 cellsVictor A Hernandez, Jessika Carvajal-Moreno, Xinyi Wang, et al.
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