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Anti-Cancer Drugs|August 24, 2006
Kinamycins A and C, bacterial metabolites that contain an unusual diazo group, as potential new anticancer agents: antiproliferative and cell cycle effectsBrian B Hasinoff, Xing Wu, Jack C Yalowich, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 20, 2024
Use of CRISPR/Cas9 with Homology-Directed Repair to Gene-Edit Topoisomerase IIβ in Human Leukemia K562 Cells: Generation of a Resistance PhenotypeJessika Carvajal-Moreno, Xinyi Wang, Victor A Hernandez, et al.
Bioorganic & Medicinal Chemistry|February 9, 2008
The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compoundsBrian B Hasinoff, Hong Liang, Xing Wu, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 8, 2026
Circumvention of acquired resistance to topoisomerase II-targeted anticancer agents in HL-60 leukemia cells by prevention of intronic polyadenylationXinyu Zhao, Sydney R Cassel, Sarah E Eaton, et al.
Bioorganic & Medicinal Chemistry|May 22, 2009
The structure-based design, synthesis, and biological evaluation of DNA-binding amide linked bisintercalating bisanthrapyrazole anticancer compoundsBrian B Hasinoff, Rui Zhang, Xing Wu, et al.
Molecular Pharmacology|May 8, 2024
Circumvention of Topoisomerase IIα Intron 19 Intronic Polyadenylation in Acquired Etoposide-Resistant Human Leukemia K562 CellsXinyi Wang, Jessika Carvajal-Moreno, Xinyu Zhao, et al.
Toxicology|July 20, 2002
Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants?Martin Modriansky, Yulia Y Tyurina, Vladimir A Tyurin, et al.
Bioorganic & Medicinal Chemistry|May 18, 2010
Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agentsRui Zhang, Xing Wu, Lynn J Guziec, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 16, 2016
Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa IsoformRagu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, et al.
Molecular Pharmacology|March 9, 2018
The Novel C-terminal Truncated 90-kDa Isoform of Topoisomerase IIα (TOP2α/90) Is a Determinant of Etoposide Resistance in K562 Leukemia Cells via Heterodimerization with the TOP2α/170 IsoformRagu Kanagasabai, Soumendrakrishna Karmahapatra, Corey A Kientz, et al.
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