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Molecular Metabolism|March 16, 2021
Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progressionVian Azzu, Michele Vacca, Ioannis Kamzolas, et al.
Hepatology (Baltimore, Md.)|September 11, 2022
c-Rel-dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesisJack Leslie, Jill E Hunter, Amy Collins, et al.
Hepatology (Baltimore, Md.)|June 22, 2021
Immunomodulatory Effects of Lenvatinib Plus Anti-Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular CarcinomaLaura Torrens, Carla Montironi, Marc Puigvehí, et al.
Rheumatology (Oxford, England)|July 30, 2020
cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosisJulie C Worrell, Jack Leslie, Graham R Smith, et al.
Nature Metabolism|July 23, 2020
Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitisMichele Vacca, Jack Leslie, Samuel Virtue, et al.
Scientific Reports|August 19, 2021
Key features of the environment promoting liver cancer in the absence of cirrhosisMarco Youssef William Zaki, Ahmed Khairallah Mahdi, Gillian Lucinda Patman, et al.
Communications Biology|March 6, 2024
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancerRebecca Garnham, Daniel Geh, Ryan Nelson, et al.
Metabolism: Clinical and Experimental|March 24, 2025
Spatial lipidomics reveals sphingolipid metabolism as anti-fibrotic target in the liverAleksandra Gruevska, Jack Leslie, Elena Perpiñán, et al.
JCI Insight|February 28, 2020
FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosisJack Leslie, Ben Jm Millar, Alicia Del Carpio Pons, et al.
Hepatology (Baltimore, Md.)|April 10, 2019
A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver SlicesHannah L Paish, Lee H Reed, Helen Brown, et al.
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