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Liver Cancer|January 2, 2023
Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?Marco Y W Zaki, Sari F Alhasan, Ruchi Shukla, et al.
Biorxiv : the Preprint Server for Biology|July 14, 2025
Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axisBruno Beernaert, Rose L Jady-Clark, Parin Shah, et al.
Nature Cancer|October 19, 2020
Age-associated mitochondrial DNA mutations cause metabolic remodelling that contributes to accelerated intestinal tumorigenesisAnna Lm Smith, Julia C Whitehall, Carla Bradshaw, et al.
Science Advances|March 11, 2026
Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axisBruno Beernaert, Rose L Jady-Clark, Parin Shah, et al.
The American Journal of Pathology|October 15, 2022
Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated MiceLucy M V Gee, Ben Barron-Millar, Jack Leslie, et al.
The EMBO Journal|March 25, 2021
Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent mannerAnthony Lagnado, Jack Leslie, Marie-Helene Ruchaud-Sparagano, et al.
Nature Metabolism|September 25, 2024
Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver healthSam M Lockhart, Milan Muso, Ilona Zvetkova, et al.
Nature Metabolism|November 10, 2020
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosisJack Leslie, Marina García Macia, Saimir Luli, et al.
Nature|February 19, 2025
Human-correlated genetic models identify precision therapy for liver cancerMiryam Müller, Stephanie May, Holly Hall, et al.
Gut|April 28, 2022
CXCR2 inhibition enables NASH-HCC immunotherapyJack Leslie, John B G Mackey, Thomas Jamieson, et al.
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