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Jack U Flanagan

Showing results (41-50 of 64) with videos related to

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Bioorganic & Medicinal Chemistry|January 9, 2014
Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3)Darby G Brooke, Ellen M van Dam, Colin K W Watts, et al.
Cell Chemical Biology|March 7, 2017
Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene TherapyJanine N Copp, Alexandra M Mowday, Elsie M Williams, et al.
European Journal of Medicinal Chemistry|November 27, 2009
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthaseJane E Weber, Aaron J Oakley, Angelika N Christ, et al.
The Journal of Biological Chemistry|September 16, 2005
Why is quinidine an inhibitor of cytochrome P450 2D6? The role of key active-site residues in quinidine bindingLesley A McLaughlin, Mark J I Paine, Carol A Kemp, et al.
Bioorganic & Medicinal Chemistry|November 23, 2013
Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)Sai-Parng S Fung, Haiyan Wang, Petr Tomek, et al.
Chemistry, an Asian Journal|February 5, 2019
Synthesis and Evaluation of Imidazo[1,2-a]pyridine Analogues of the ZSTK474 Class of Phosphatidylinositol 3-Kinase InhibitorsSwarna A Gamage, Julie A Spicer, Kit Y Tsang, et al.
The Biochemical Journal|June 15, 2011
A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell typesStephen Jamieson, Jack U Flanagan, Sharada Kolekar, et al.
Bioorganic & Medicinal Chemistry|April 20, 2015
Exploring the isoform selectivity of TGX-221 related pyrido[1,2-a]pyrimidinone-based Class IA PI 3-kinase inhibitors: synthesis, biological evaluation and molecular modellingAndrew J Marshall, Claire L Lill, Mindy Chao, et al.
Bioorganic & Medicinal Chemistry|January 14, 2014
Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3)Jack U Flanagan, Graham J Atwell, Daniel M Heinrich, et al.
Biochemistry|August 13, 2019
Engineering <i>Escherichia coli</i> NfsB To Activate a Hypoxia-Resistant Analogue of the PET Probe EF5 To Enable Non-Invasive Imaging during Enzyme Prodrug TherapyElsie M Williams, Michelle H Rich, Alexandra M Mowday, et al.
Pageof 7

Showing results (41-50 of 64) with videos related to

Sort By:
Pageof 7
Bioorganic & Medicinal Chemistry|January 9, 2014
Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3)Darby G Brooke, Ellen M van Dam, Colin K W Watts, et al.
Cell Chemical Biology|March 7, 2017
Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene TherapyJanine N Copp, Alexandra M Mowday, Elsie M Williams, et al.
European Journal of Medicinal Chemistry|November 27, 2009
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthaseJane E Weber, Aaron J Oakley, Angelika N Christ, et al.
The Journal of Biological Chemistry|September 16, 2005
Why is quinidine an inhibitor of cytochrome P450 2D6? The role of key active-site residues in quinidine bindingLesley A McLaughlin, Mark J I Paine, Carol A Kemp, et al.
Bioorganic & Medicinal Chemistry|November 23, 2013
Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)Sai-Parng S Fung, Haiyan Wang, Petr Tomek, et al.
Chemistry, an Asian Journal|February 5, 2019
Synthesis and Evaluation of Imidazo[1,2-a]pyridine Analogues of the ZSTK474 Class of Phosphatidylinositol 3-Kinase InhibitorsSwarna A Gamage, Julie A Spicer, Kit Y Tsang, et al.
The Biochemical Journal|June 15, 2011
A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell typesStephen Jamieson, Jack U Flanagan, Sharada Kolekar, et al.
Bioorganic & Medicinal Chemistry|April 20, 2015
Exploring the isoform selectivity of TGX-221 related pyrido[1,2-a]pyrimidinone-based Class IA PI 3-kinase inhibitors: synthesis, biological evaluation and molecular modellingAndrew J Marshall, Claire L Lill, Mindy Chao, et al.
Bioorganic & Medicinal Chemistry|January 14, 2014
Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3)Jack U Flanagan, Graham J Atwell, Daniel M Heinrich, et al.
Biochemistry|August 13, 2019
Engineering <i>Escherichia coli</i> NfsB To Activate a Hypoxia-Resistant Analogue of the PET Probe EF5 To Enable Non-Invasive Imaging during Enzyme Prodrug TherapyElsie M Williams, Michelle H Rich, Alexandra M Mowday, et al.
Pageof 7