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Mathematical Biosciences
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March 18, 2014
Stochastic differential equations as a tool to regularize the parameter estimation problem for continuous time dynamical systems given discrete time measurements
Jacob Leander, Torbjörn Lundh, Mats Jirstrand
Pharmacology Research & Perspectives
|
May 8, 2026
Population Pharmacokinetics of the Novel Myeloperoxidase Inhibitor Mitiperstat
Mikael Sunnåker, Jacob Leander, Hans Ericsson
Clinical Pharmacokinetics
|
September 20, 2020
Higher Febuxostat Exposure Observed in Asian Compared with Caucasian Subjects Independent of Bodyweight
Dinko Rekić, Susanne Johansson, Jacob Leander
Journal of Pharmacokinetics and Pharmacodynamics
|
March 25, 2015
Using sensitivity equations for computing gradients of the FOCE and FOCEI approximations to the population likelihood
Joachim Almquist, Jacob Leander, Mats Jirstrand
The AAPS Journal
|
August 3, 2018
Exact Gradients Improve Parameter Estimation in Nonlinear Mixed Effects Models with Stochastic Dynamics
Helga Kristin Olafsdottir, Jacob Leander, Joachim Almquist, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 19, 2021
A stochastic mixed effects model to assess treatment effects and fluctuations in home-measured peak expiratory flow and the association with exacerbation risk in asthma
Jacob Leander, Mats Jirstrand, Ulf G Eriksson, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
June 6, 2026
Modeling Peak Expiratory Flow in Patients With Asthma and Quantifying Treatment Effects Using a Mixed-Effects Hidden Markov Model
Ludvig Jakobsson, Marcus Baaz, Jacob Leander, et al.
The AAPS Journal
|
February 20, 2015
Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker Rats
Jacob Leander, Joachim Almquist, Christine Ahlström, et al.
Statistics in Medicine
|
March 13, 2026
Location-Scale Latent Process Model for Repeated Ordinal Patient-Reported Outcomes
Agnieszka Król, Robert Palmér, Jacob Leander, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
March 17, 2021
A semi-mechanistic exposure-response model to assess the effects of verinurad, a potent URAT1 inhibitor, on serum and urine uric acid in patients with hyperuricemia-associated diseases
Jacob Leander, Mikael Sunnåker, Dinko Rekić, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 17) with videos related to
Sort By:
Page
of 2
Mathematical Biosciences
|
March 18, 2014
Stochastic differential equations as a tool to regularize the parameter estimation problem for continuous time dynamical systems given discrete time measurements
Jacob Leander, Torbjörn Lundh, Mats Jirstrand
Pharmacology Research & Perspectives
|
May 8, 2026
Population Pharmacokinetics of the Novel Myeloperoxidase Inhibitor Mitiperstat
Mikael Sunnåker, Jacob Leander, Hans Ericsson
Clinical Pharmacokinetics
|
September 20, 2020
Higher Febuxostat Exposure Observed in Asian Compared with Caucasian Subjects Independent of Bodyweight
Dinko Rekić, Susanne Johansson, Jacob Leander
Journal of Pharmacokinetics and Pharmacodynamics
|
March 25, 2015
Using sensitivity equations for computing gradients of the FOCE and FOCEI approximations to the population likelihood
Joachim Almquist, Jacob Leander, Mats Jirstrand
The AAPS Journal
|
August 3, 2018
Exact Gradients Improve Parameter Estimation in Nonlinear Mixed Effects Models with Stochastic Dynamics
Helga Kristin Olafsdottir, Jacob Leander, Joachim Almquist, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 19, 2021
A stochastic mixed effects model to assess treatment effects and fluctuations in home-measured peak expiratory flow and the association with exacerbation risk in asthma
Jacob Leander, Mats Jirstrand, Ulf G Eriksson, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
June 6, 2026
Modeling Peak Expiratory Flow in Patients With Asthma and Quantifying Treatment Effects Using a Mixed-Effects Hidden Markov Model
Ludvig Jakobsson, Marcus Baaz, Jacob Leander, et al.
The AAPS Journal
|
February 20, 2015
Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker Rats
Jacob Leander, Joachim Almquist, Christine Ahlström, et al.
Statistics in Medicine
|
March 13, 2026
Location-Scale Latent Process Model for Repeated Ordinal Patient-Reported Outcomes
Agnieszka Król, Robert Palmér, Jacob Leander, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
March 17, 2021
A semi-mechanistic exposure-response model to assess the effects of verinurad, a potent URAT1 inhibitor, on serum and urine uric acid in patients with hyperuricemia-associated diseases
Jacob Leander, Mikael Sunnåker, Dinko Rekić, et al.
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