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Jacob Piehler

Showing results (161-170 of 177) with videos related to

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Molecular Therapy : the Journal of the American Society of Gene Therapy|August 31, 2025
Tuning of G-CSFR signaling by de novo designed agonistsTimo Ullrich, Christoph Pollmann, Malte Ritter, et al.
Nature|June 11, 2015
Supramolecular assemblies underpin turnover of outer membrane proteins in bacteriaPatrice Rassam, Nikki A Copeland, Oliver Birkholz, et al.
Nature|May 4, 2017
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signallingClaudia Y Janda, Luke T Dang, Changjiang You, et al.
Elife|September 14, 2022
Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathwayTolulope Sokoya, Jan Parolek, Mads Møller Foged, et al.
The Journal of Biological Chemistry|August 17, 2021
Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNAHai Pan, Parminder Kaur, Ryan Barnes, et al.
Cell|March 3, 2015
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligandsIgnacio Moraga, Gerlinde Wernig, Stephan Wilmes, et al.
Science (New York, N.Y.)|February 8, 2020
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutationsStephan Wilmes, Maximillian Hafer, Joni Vuorio, et al.
Elife|May 18, 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonistCaleb R Glassman, Leon Su, Sonia S Majri-Morrison, et al.
Science Immunology|December 2, 2022
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective muteinSilvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani, et al.
Biorxiv : the Preprint Server for Biology|November 28, 2024
Design of facilitated dissociation enables control over cytokine signaling durationAdam J Broerman, Christoph Pollmann, Mauriz A Lichtenstein, et al.
Pageof 18

Showing results (161-170 of 177) with videos related to

Sort By:
Pageof 18
Molecular Therapy : the Journal of the American Society of Gene Therapy|August 31, 2025
Tuning of G-CSFR signaling by de novo designed agonistsTimo Ullrich, Christoph Pollmann, Malte Ritter, et al.
Nature|June 11, 2015
Supramolecular assemblies underpin turnover of outer membrane proteins in bacteriaPatrice Rassam, Nikki A Copeland, Oliver Birkholz, et al.
Nature|May 4, 2017
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signallingClaudia Y Janda, Luke T Dang, Changjiang You, et al.
Elife|September 14, 2022
Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathwayTolulope Sokoya, Jan Parolek, Mads Møller Foged, et al.
The Journal of Biological Chemistry|August 17, 2021
Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNAHai Pan, Parminder Kaur, Ryan Barnes, et al.
Cell|March 3, 2015
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligandsIgnacio Moraga, Gerlinde Wernig, Stephan Wilmes, et al.
Science (New York, N.Y.)|February 8, 2020
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutationsStephan Wilmes, Maximillian Hafer, Joni Vuorio, et al.
Elife|May 18, 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonistCaleb R Glassman, Leon Su, Sonia S Majri-Morrison, et al.
Science Immunology|December 2, 2022
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective muteinSilvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani, et al.
Biorxiv : the Preprint Server for Biology|November 28, 2024
Design of facilitated dissociation enables control over cytokine signaling durationAdam J Broerman, Christoph Pollmann, Mauriz A Lichtenstein, et al.
Pageof 18