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Neuron|July 23, 2021
RNA modulates physiological and neuropathological protein phase transitionsJacob R Mann, Christopher J DonnellyInvestigative Ophthalmology & Visual Science|July 2, 2016
Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in RatsSteven Roth, John C Dreixler, Biji Mathew, et al.Neurobiology of Disease|September 14, 2020
Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivoCharlton G Otte, Tyler R Fortuna, Jacob R Mann, et al.Acta Neuropathologica Communications|November 1, 2020
RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3Nandini Ramesh, Elizabeth L Daley, Amanda M Gleixner, et al.Science Advances|August 16, 2023
Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear importJacob R Mann, Elizabeth D McKenna, Darilang Mawrie, et al.Nature Communications|June 13, 2022
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubilityAmanda M Gleixner, Brandie Morris Verdone, Charlton G Otte, et al.Neuron|March 4, 2019
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, et al.Biorxiv : the Preprint Server for Biology|September 21, 2023
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domainsLin Guo, Jacob R Mann, Jocelyn C Mauna, et al.Molecular Cell|January 9, 2026
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domainsLin Guo, Jacob R Mann, Jocelyn C Mauna, et al.Nature Neuroscience|November 1, 2025
TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTDBrian J Joseph, Kelly A Marshall, Peter Harley, et al.Pageof 1