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Plos One|December 17, 2020
Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damageNealia C M House, Ramya Parasuram, Jacob V Layer, et al.Biochimica Et Biophysica Acta|October 2, 2012
Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathwayJacob V Layer, Brett M Barnes, Yuji Yamasaki, et al.The Journal of Biological Chemistry|April 15, 2011
An "exacerbate-reverse" strategy in yeast identifies histone deacetylase inhibition as a correction for cholesterol and sphingolipid transport defects in human Niemann-Pick type C diseaseAndrew B Munkacsi, Fannie W Chen, Matthew A Brinkman, et al.Proceedings of the National Academy of Sciences of the United States of America|October 20, 2020
Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repairJacob V Layer, Lydie Debaize, Alexandria Van Scoyk, et al.Nature Communications|June 26, 2026
Multiple human transgenes prolong survival of triple-carbohydrate knockout porcine kidney xenografts in nonhuman primatesAhmad Karadagi, Takayuki Hirose, Grace Lassiter, et al.Xenotransplantation|September 20, 2022
Genetic modifications designed for xenotransplantation attenuate sialoadhesin-dependent binding of human erythrocytes to porcine macrophagesKaitlyn Petitpas, Zahra Habibabady, Veronica Ritchie, et al.Nature Communications|June 14, 2017
Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNATovah A Day, Jacob V Layer, J Patrick Cleary, et al.Nature Communications|April 28, 2017
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNATovah A Day, Jacob V Layer, J Patrick Cleary, et al.Blood|October 16, 2016
HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphomaCaron Jacobson, Nadja Kopp, Jacob V Layer, et al.Proceedings of the National Academy of Sciences of the United States of America|September 15, 2018
Parp3 promotes long-range end joining in murine cellsJacob V Layer, J Patrick Cleary, Alexander J Brown, et al.Pageof 2