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Journal of Medicinal Chemistry|April 22, 2009
Mapping adverse drug reactions in chemical spaceJosef Scheiber, Jeremy L Jenkins, Sai Chetan K Sukuru, et al.Bioorganic & Medicinal Chemistry Letters|June 4, 2013
Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluationPascal Furet, Vito Guagnano, Robin A Fairhurst, et al.Nature|June 23, 2012
Large-scale prediction and testing of drug activity on side-effect targetsEugen Lounkine, Michael J Keiser, Steven Whitebread, et al.Bioorganic & Medicinal Chemistry Letters|July 9, 2005
Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitorsAnne-Claude Dublanchet, Pierre Ducrot, Charles Andrianjara, et al.Journal of Chemical Information and Modeling|May 13, 2009
Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysisJosef Scheiber, Bin Chen, Mariusz Milik, et al.Chemmedchem|February 9, 2024
Challenges for the Discovery of Non-Covalent WRN Helicase InhibitorsAlisa Heuser, Wassim Abdul Rahman, Elisabeth Bechter, et al.The Journal of Biological Chemistry|August 14, 2013
Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cellsSebastien Hannedouche, Valerie Beck, Juliet Leighton-Davies, et al.Nature|April 24, 2024
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancersStephane Ferretti, Jacques Hamon, Ruben de Kanter, et al.Nature Communications|April 27, 2021
PAX8 and MECOM are interaction partners driving ovarian cancerMelusine Bleu, Fanny Mermet-Meillon, Verena Apfel, et al.Pageof 2