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Addiction Biology|November 22, 2019
25B-NBOMe, a novel N-2-methoxybenzyl-phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potentialRaly James Perez Custodio, Leandro Val Sayson, Chrislean Jun Botanas, et al.
Biomolecules & Therapeutics|February 8, 2017
The Abuse Potential of α-Piperidinopropiophenone (PIPP) and α-Piperidinopentiothiophenone (PIVT), Two New Synthetic Cathinones with Piperidine Ring SubstituentChrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, et al.
Pharmacology, Biochemistry, and Behavior|January 9, 2017
The abuse potential of two novel synthetic cathinones with modification on the alpha-carbon position, 2-cyclohexyl-2-(methylamino)-1-phenylethanone (MACHP) and 2-(methylamino)-1-phenyloctan-1-one (MAOP), and their effects on dopaminergic activityChrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, et al.
Behavioural Brain Research|October 15, 2016
A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in miceChrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, et al.
Psychopharmacology|March 21, 2019
The novel methoxetamine analogs N-ethylnorketamine hydrochloride (NENK), 2-MeO-N-ethylketamine hydrochloride (2-MeO-NEK), and 4-MeO-N-ethylketamine hydrochloride (4-MeO-NEK) elicit rapid antidepressant effects via activation of AMPA and 5-HT2 receptorsLeandro Val Sayson, Chrislean Jun Botanas, Raly James Perez Custodio, et al.
Neuropharmacology|May 23, 2021
R (-)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamineChrislean Jun Botanas, Raly James Perez Custodio, Hee Jin Kim, et al.
Behavioural Brain Research|December 31, 2017
A new synthetic drug 5-(2-aminopropyl)indole (5-IT) induces rewarding effects and increases dopamine D1 receptor and dopamine transporter mRNA levelsChrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, et al.
Biomolecules & Therapeutics|June 25, 2019
Four Novel Synthetic Tryptamine Analogs Induce Head-Twitch Responses and Increase 5-HTR2a in the Prefrontal Cortex in MiceArvie Abiero, In Soo Ryu, Chrislean Jun Botanas, et al.
Behavioural Brain Research|July 28, 2018
5-Methoxy-α-methyltryptamine (5-MeO-AMT), a tryptamine derivative, induces head-twitch responses in mice through the activation of serotonin receptor 2a in the prefrontal cortexArvie Abiero, Chrislean Jun Botanas, Leandro Val Sayson, et al.
Biomolecules & Therapeutics|October 31, 2017
Evaluation of the Abuse Potential of Novel Amphetamine Derivatives with Modifications on the Amine (NBNA) and Phenyl (EDA, PMEA, 2-APN) SitesRaly James Perez Custodio, Chrislean Jun Botanas, Seong Shoon Yoon, et al.
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