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Science (New York, N.Y.)|October 14, 2021
CD4+ T cells contribute to neurodegeneration in Lewy body dementiaDavid Gate, Emma Tapp, Olivia Leventhal, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|April 12, 2013
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal lossRobert M Cohen, Kavon Rezai-Zadeh, Tara M Weitz, et al.Neuron|January 14, 2025
Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healingGuiping Kong, Yayue Song, Yuyang Yan, et al.Nature|April 5, 2019
CD22 blockade restores homeostatic microglial phagocytosis in ageing brainsJohn V Pluvinage, Michael S Haney, Benjamin A H Smith, et al.Cell|December 14, 2022
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairmentNatalie Piehl, Lynn van Olst, Abhirami Ramakrishnan, et al.The Journal of Clinical Investigation|May 13, 2025
The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17Sidhanth Chandra, Jelena Popovic, Naveen K Singhal, et al.Nature|January 10, 2020
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's diseaseDavid Gate, Naresha Saligrama, Olivia Leventhal, et al.Science Translational Medicine|December 1, 2021
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type CJohn V Pluvinage, Jerry Sun, Christel Claes, et al.Nature|June 21, 2021
Dysregulation of brain and choroid plexus cell types in severe COVID-19Andrew C Yang, Fabian Kern, Patricia M Losada, et al.Immunity|May 1, 2025
Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microgliaJonathan Bastos, Carleigh O'Brien, Mónica Vara-Pérez, et al.Pageof 6