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Jakub Scaber

Showing results (11-20 of 24) with videos related to

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Expert Opinion on Drug Discovery|March 3, 2025
Drug repurposing in amyotrophic lateral sclerosis (ALS)Emily Carroll, Jakub Scaber, Kilian V M Huber, et al.
Cell Stem Cell|January 7, 2022
Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translationElisa Giacomelli, Björn F Vahsen, Elizabeth L Calder, et al.
Brain Communications|October 23, 2024
Dynactin-1 mediates rescue of impaired axonal transport due to reduced mitochondrial bioenergetics in amyotrophic lateral sclerosis motor neuronsRuxandra Dafinca, Carlota Tosat-Bitrian, Emily Carroll, et al.
Stem Cell Reports|April 25, 2020
Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTDRuxandra Dafinca, Paola Barbagallo, Lucy Farrimond, et al.
Human Molecular Genetics|June 7, 2020
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repairNidaa A Ababneh, Jakub Scaber, Rowan Flynn, et al.
Stem Cell Reports|June 14, 2024
Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neuronsJakub Scaber, Iona Thomas-Wright, Alex J Clark, et al.
Neurobiology of Disease|October 6, 2018
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunctionDavid Gordon, Ruxandra Dafinca, Jakub Scaber, et al.
Scientific Reports|July 23, 2022
Human iPSC co-culture model to investigate the interaction between microglia and motor neuronsBjörn F Vahsen, Elizabeth Gray, Ana Candalija, et al.
Ebiomedicine|June 27, 2018
Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral SclerosisMatthew Salter, Emily Corfield, Aroul Ramadass, et al.
Stem Cells (Dayton, Ohio)|April 21, 2016
C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal DementiaRuxandra Dafinca, Jakub Scaber, Nida'a Ababneh, et al.
Pageof 3

Showing results (11-20 of 24) with videos related to

Sort By:
Pageof 3
Expert Opinion on Drug Discovery|March 3, 2025
Drug repurposing in amyotrophic lateral sclerosis (ALS)Emily Carroll, Jakub Scaber, Kilian V M Huber, et al.
Cell Stem Cell|January 7, 2022
Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translationElisa Giacomelli, Björn F Vahsen, Elizabeth L Calder, et al.
Brain Communications|October 23, 2024
Dynactin-1 mediates rescue of impaired axonal transport due to reduced mitochondrial bioenergetics in amyotrophic lateral sclerosis motor neuronsRuxandra Dafinca, Carlota Tosat-Bitrian, Emily Carroll, et al.
Stem Cell Reports|April 25, 2020
Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTDRuxandra Dafinca, Paola Barbagallo, Lucy Farrimond, et al.
Human Molecular Genetics|June 7, 2020
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repairNidaa A Ababneh, Jakub Scaber, Rowan Flynn, et al.
Stem Cell Reports|June 14, 2024
Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neuronsJakub Scaber, Iona Thomas-Wright, Alex J Clark, et al.
Neurobiology of Disease|October 6, 2018
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunctionDavid Gordon, Ruxandra Dafinca, Jakub Scaber, et al.
Scientific Reports|July 23, 2022
Human iPSC co-culture model to investigate the interaction between microglia and motor neuronsBjörn F Vahsen, Elizabeth Gray, Ana Candalija, et al.
Ebiomedicine|June 27, 2018
Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral SclerosisMatthew Salter, Emily Corfield, Aroul Ramadass, et al.
Stem Cells (Dayton, Ohio)|April 21, 2016
C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal DementiaRuxandra Dafinca, Jakub Scaber, Nida'a Ababneh, et al.
Pageof 3