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Bioorganic & Medicinal Chemistry Letters|July 22, 2015
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potencyMelissa Egbertson, Georgia B McGaughey, Steven M Pitzenberger, et al.Journal of Medicinal Chemistry|June 11, 2008
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonistWilliam D Shipe, James C Barrow, Zhi-Qiang Yang, et al.Journal of Medicinal Chemistry|September 27, 2008
Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channelsZhi-Qiang Yang, James C Barrow, William D Shipe, et al.Journal of Medicinal Chemistry|February 7, 2003
Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridinesChristopher S Burgey, Kyle A Robinson, Terry A Lyle, et al.Nature Communications|January 25, 2020
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCsEmily E Burke, Joshua G Chenoweth, Joo Heon Shin, et al.Pageof 7