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Cancer Chemotherapy and Pharmacology|December 19, 2024
Absorption, single-dose and steady-state metabolism, excretion, and pharmacokinetics of adagrasib, a KRASG12C inhibitorLisa Rahbaek, Cornelius Cilliers, Christopher J Wegerski, et al.
Neuro-Oncology|February 25, 2010
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinibManik Chahal, Yaoxian Xu, David Lesniak, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 3, 2008
Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse modelsShinji Yamazaki, Judith Skaptason, David Romero, et al.
Neoplasia (New York, N.Y.)|November 30, 2006
Inhibition of c-Met as a therapeutic strategy for esophageal adenocarcinomaGregory A Watson, Xinglu Zhang, Michael T Stang, et al.
Stem Cells Translational Medicine|February 15, 2013
Synergistic effect of the γ-secretase inhibitor PF-03084014 and docetaxel in breast cancer modelsCathy C Zhang, Zhengming Yan, Qing Zong, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 12, 2004
A selective c-met inhibitor blocks an autocrine hepatocyte growth factor growth loop in ANBL-6 cells and prevents migration and adhesion of myeloma cellsHåkon Hov, Randi Utne Holt, Torstein Baade Rø, et al.
Molecular Cancer Therapeutics|December 20, 2007
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphomaJames G Christensen, Helen Y Zou, Maria E Arango, et al.
Neurological Research|March 28, 2012
The addition of Sunitinib to radiation delays tumor growth in a murine model of glioblastomaRandy D'Amico, Liang Lei, Benjamin C Kennedy, et al.
Cancer Research|November 23, 2012
Resistance to irreversible EGF receptor tyrosine kinase inhibitors through a multistep mechanism involving the IGF1R pathwayAlexis B Cortot, Claire E Repellin, Takeshi Shimamura, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|July 19, 2011
Differential (18)F-FDG and 3'-deoxy-3'-(18)F-fluorothymidine PET responses to pharmacologic inhibition of the c-MET receptor in preclinical tumor modelsCarleen Cullinane, Donna S Dorow, Susan Jackson, et al.
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