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Cancer Research|October 30, 2010
The neuroblastoma-associated F1174L ALK mutation causes resistance to an ALK kinase inhibitor in ALK-translocated cancersTakaaki Sasaki, Katsuhiro Okuda, Wei Zheng, et al.
Science Translational Medicine|February 4, 2026
Kras G12C- and G12D-driven lung cancers differ in oncogenic potency, immunogenicity, and relapse after Kras inhibition in mouse modelsHai-Cheng Huang, Qing Deng, Lei Guo, et al.
Cancer Research|March 1, 2005
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancerPatrick C Ma, Ramasamy Jagadeeswaran, Simha Jagadeesh, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|July 9, 2009
PF-00477736 mediates checkpoint kinase 1 signaling pathway and potentiates docetaxel-induced efficacy in xenograftsCathy Zhang, Zhengming Yan, Cory L Painter, et al.
RSC Medicinal Chemistry|December 22, 2022
Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hitsChristopher R Smith, Svitlana Kulyk, Misbha Ud Din Ahmad, et al.
Targeted Oncology|December 2, 2022
Phase I Study Evaluating Glesatinib (MGCD265), An Inhibitor of MET and AXL, in Patients with Non-small Cell Lung Cancer and Other Advanced Solid TumorsChristian Kollmannsberger, Herbert Hurwitz, Lyudmila Bazhenova, et al.
Oncotarget|September 23, 2016
Targeting MET and EGFR crosstalk signaling in triple-negative breast cancersErik S Linklater, Elizabeth A Tovar, Curt J Essenburg, et al.
Cancer Research|November 13, 2003
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivoJames G Christensen, Randall Schreck, Jon Burrows, et al.
Molecular Cancer Therapeutics|March 16, 2021
The KRASG12C Inhibitor MRTX849 Reconditions the Tumor Immune Microenvironment and Sensitizes Tumors to Checkpoint Inhibitor TherapyDavid M Briere, Shuai Li, Andrew Calinisan, et al.
Science Translational Medicine|November 11, 2011
Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastomaScott C Bresler, Andrew C Wood, Elizabeth A Haglund, et al.
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