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Plos One|November 28, 2012
Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonistJames Mu, Sajjad A Qureshi, Edward J Brady, et al.JCI Insight|January 12, 2018
A glucose-responsive insulin therapy protects animals against hypoglycemiaRuojing Yang, Margaret Wu, Songnian Lin, et al.The Journal of Clinical Investigation|January 4, 2003
The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivityBenoit Viollet, Fabrizio Andreelli, Sebastian B Jørgensen, et al.Plos One|September 17, 2013
Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21Eric S Muise, Sandra Souza, An Chi, et al.ACS Medicinal Chemistry Letters|July 14, 2026
Discovery of Biased Dual-Agonists of Glucagon-Like Peptide 1 and Glucagon Receptors through Mutation of a Conserved AspartateRobert E Thompson, Aditya J Desai, Dmitri Pissarnitski, et al.Diabetes|November 4, 2017
Engineering Glucose Responsiveness Into InsulinNiels C Kaarsholm, Songnian Lin, Lin Yan, et al.Diabetes|January 3, 2012
FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodentsJames Mu, Jason Pinkstaff, Zhihua Li, et al.Nature Communications|February 18, 2022
Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonistsMargaret Wu, Ester Carballo-Jane, Haihong Zhou, et al.Journal of Medicinal Chemistry|March 17, 2022
Discovery of Insulin Receptor Partial Agonists MK-5160 and MK-1092 as Novel Basal Insulins with Potential to Improve Therapeutic IndexDmitri A Pissarnitski, Ahmet Kekec, Lin Yan, et al.Pageof 3