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James R Halpert

Showing results (11-20 of 108) with videos related to

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Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 22, 2006
Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesisSantosh Kumar, Hong Liu, James R Halpert
Archives of Biochemistry and Biophysics|December 5, 2002
Analysis of homotropic and heterotropic cooperativity of diazepam oxidation by CYP3A4 using site-directed mutagenesis and kinetic modelingYou Ai He, Fabienne Roussel, James R Halpert
Archives of Biochemistry and Biophysics|December 19, 2007
Kinetics of electron transfer in the complex of cytochrome P450 3A4 with the flavin domain of cytochrome P450BM-3 as evidence of functional heterogeneity of the heme proteinHarshica Fernando, James R Halpert, Dmitri R Davydov
International Journal of Molecular Sciences|March 30, 2018
Crystal Structure of CYP2B6 in Complex with an Efavirenz AnalogManish B Shah, Qinghai Zhang, James R Halpert
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 19, 2003
Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration studyKishore K Khan, Hong Liu, James R Halpert
Biochemical and Biophysical Research Communications|June 14, 2002
Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrateDmitri R Davydov, Santosh Kumar, James R Halpert
Biophysical Chemistry|May 17, 2006
Variable path length and counter-flow continuous variation methods for the study of the formation of high-affinity complexes by absorbance spectroscopy. An application to the studies of substrate binding in cytochrome P450Dmitri R Davydov, Harshica Fernando, James R Halpert
Biochemistry|March 29, 2006
Resolution of multiple substrate binding sites in cytochrome P450 3A4: the stoichiometry of the enzyme-substrate complexes probed by FRET and Job's titrationHarshica Fernando, James R Halpert, Dmitri R Davydov
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 5, 2005
Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneitySantosh Kumar, Dmitri R Davydov, James R Halpert
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 17, 2008
Decreased susceptibility of the cytochrome P450 2B6 variant K262R to inhibition by several clinically important drugsJyothi C Talakad, Santosh Kumar, James R Halpert
Pageof 11

Showing results (11-20 of 108) with videos related to

Sort By:
Pageof 11
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 22, 2006
Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesisSantosh Kumar, Hong Liu, James R Halpert
Archives of Biochemistry and Biophysics|December 5, 2002
Analysis of homotropic and heterotropic cooperativity of diazepam oxidation by CYP3A4 using site-directed mutagenesis and kinetic modelingYou Ai He, Fabienne Roussel, James R Halpert
Archives of Biochemistry and Biophysics|December 19, 2007
Kinetics of electron transfer in the complex of cytochrome P450 3A4 with the flavin domain of cytochrome P450BM-3 as evidence of functional heterogeneity of the heme proteinHarshica Fernando, James R Halpert, Dmitri R Davydov
International Journal of Molecular Sciences|March 30, 2018
Crystal Structure of CYP2B6 in Complex with an Efavirenz AnalogManish B Shah, Qinghai Zhang, James R Halpert
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 19, 2003
Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration studyKishore K Khan, Hong Liu, James R Halpert
Biochemical and Biophysical Research Communications|June 14, 2002
Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrateDmitri R Davydov, Santosh Kumar, James R Halpert
Biophysical Chemistry|May 17, 2006
Variable path length and counter-flow continuous variation methods for the study of the formation of high-affinity complexes by absorbance spectroscopy. An application to the studies of substrate binding in cytochrome P450Dmitri R Davydov, Harshica Fernando, James R Halpert
Biochemistry|March 29, 2006
Resolution of multiple substrate binding sites in cytochrome P450 3A4: the stoichiometry of the enzyme-substrate complexes probed by FRET and Job's titrationHarshica Fernando, James R Halpert, Dmitri R Davydov
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 5, 2005
Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneitySantosh Kumar, Dmitri R Davydov, James R Halpert
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 17, 2008
Decreased susceptibility of the cytochrome P450 2B6 variant K262R to inhibition by several clinically important drugsJyothi C Talakad, Santosh Kumar, James R Halpert
Pageof 11